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Eosinophil Count (Manual Differential Blood Count)

Published: August 9, 2026Updated: August 16, 2026

This test measures the number of eosinophils, a type of white blood cell, in your blood. Eosinophils help fight certain infections and respond to allergic reactions.

Quick summary

["Eosinophils can signal inflammation or allergic responses, helping doctors diagnose conditions like allergies or infections."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
40569-6
Short code
Eosinophil # Fld Manual
Synonyms
Eosinophil # Fld Manual
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
manual-count
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Is Done

Your doctor may order this test if you have symptoms like persistent itching, skin rashes, asthma, or unexplained infections. It can also help monitor conditions like parasitic infections, certain cancers, or allergic disorders.

What to Expect Before the Test

No special preparation is needed. A blood sample is taken from a vein, usually in your arm, and sent to the lab for manual counting of eosinophils under a microscope.

What the Results Mean

Results are expressed as a count of eosinophils per microliter (µL) of blood. Higher-than-normal counts may indicate allergies, infections, or other inflammatory conditions. Lower-than-normal counts may suggest immune suppression or other health issues.

Possible Conditions Linked to Eosinophil Levels

Elevated eosinophil counts can be linked to allergies, asthma, parasitic infections, certain cancers (like leukemia), or autoimmune diseases. Low levels may be associated with immune disorders or chronic illnesses.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical significance: Eosinophils play a key role in defending against parasites and managing allergic reactions. Elevated levels often point to ongoing inflammation or immune responses, guiding treatment for conditions like asthma, allergies, or parasitic infections. Doctors use these results to tailor therapies and monitor disease activity.

Short name

Eosinophil Level

Frequently asked questions

What causes eosinophil levels to rise?
Elevated eosinophil counts can result from allergies, asthma, parasitic infections, certain cancers, or autoimmune diseases. Stress or certain medications may also temporarily affect levels.
What happens if my eosinophil count is high?
If your count is high, your doctor may recommend treatments for the underlying cause, such as allergy medications, anti-inflammatory drugs, or further testing for infections or cancers.
Can I eat or drink before this test?
No special diet or fasting is required for this test. However, inform your doctor about any medications or supplements you’re taking, as they may affect blood cell counts.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy