Eosinophil count in cerebrospinal fluid (CSF)
This test measures the number of eosinophils, a type of white blood cell, in your cerebrospinal fluid (the fluid surrounding the brain and spinal cord).
["Eosinophils in CSF may indicate certain infections or inflammatory conditions."]
Key facts at a glance
- LOINC
- 26451-5
- Short code
- Eosinophil NFr CSF
- Synonyms
- Eosinophil NFr CSF
- Category
- chemistry
- Sample
- csf
- Container
- Sterile tube
- Units
- N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Specimen volume
- 1-2 mL
- Stability
- Immediate analysis required, Refrigerated: 1h
- Hemolysis max
- 200
- TAT
- 4–24 hours
- Order
- routine
What Is Eosinophil Count Used For?
Eosinophils are typically found in lower amounts in cerebrospinal fluid under normal conditions. When elevated, they may suggest conditions like parasitic infections, certain fungal infections, or inflammatory diseases such as sarcoidosis. This test helps doctors diagnose or monitor these conditions by examining fluid collected through a spinal tap.
When Might You Need This Test?
Your doctor may order this test if you have symptoms like severe headaches, neck stiffness, nausea, or if they suspect a condition affecting the central nervous system. It’s also used in cases where other tests or symptoms point toward eosinophilic meningitis or other eosinophil-related disorders.
How Is the Test Performed?
A small amount of cerebrospinal fluid is collected through a procedure called a lumbar puncture (spinal tap). The fluid is then sent to a lab for analysis, where eosinophils are counted under a microscope.
What Are Possible Results?
Results are typically reported as the number of eosinophils per microliter (µL) of CSF. While specific reference ranges can vary, elevated counts (above normal baseline) are key to identifying potential issues.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
Elevated eosinophil counts in CSF are often associated with parasitic infections (e.g., filariasis), certain fungal infections, or autoimmune/inflammatory conditions like eosinophilic meningitis. Low or normal counts usually indicate no significant eosinophilic activity unless other symptoms or tests support an alternative diagnosis.
Short name
CSF Eosinophil Count
Frequently asked questions
Why might my doctor suspect eosinophils in my CSF?
How long does it take to get results from this test?
Can I take anything special before this test?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy