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Eosinophil Count (Manual Differential Blood Count)

Published: August 9, 2026Updated: August 16, 2026

This test measures the number of eosinophils, a type of white blood cell, in your blood. Eosinophils help fight infections caused by parasites and play a role in allergic reactions.

Quick summary

Eosinophils help protect your body from certain infections and allergies.

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
12210-1
Short code
Eosinophil NFr UrnS Manual
Synonyms
Eosinophil NFr UrnS Manual
Category
chemistry
Sample
urine
Container
Sterile urine container
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
manual-count
Specimen volume
10 mL
Stability
Room temperature: 2h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
0
Lipemia max
0
Icterus max
0
TAT
4–24 hours
Order
routine

Why Might You Need This Test?

Your healthcare provider may order this test to diagnose or monitor conditions like allergies, asthma, parasitic infections, or certain blood disorders. It can also help assess how your body is responding to treatments for these conditions.

What to Expect Before the Test

No special preparation is usually needed. You may be asked to fast for 8–12 hours before the test if it involves drawing blood from a vein, but this is not always required for manual differential counts. Bring any medications or supplements you’re taking to your appointment.

What Happens During the Test?

A healthcare professional will draw a small amount of blood from a vein in your arm. The blood sample is then examined under a microscope by a trained technician to count eosinophils among other white blood cells. This process is called a manual differential blood count.

What Are the Results Measured Against?

Results are typically reported as the absolute count of eosinophils per microliter (µL) of blood. While reference ranges vary by lab, elevated eosinophil counts may suggest certain conditions, and lower counts may indicate other health concerns.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Elevated eosinophil counts can signal conditions such as allergies, asthma, parasitic infections, or certain autoimmune diseases. Low eosinophil counts might be associated with infections like tuberculosis, certain cancers, or immune deficiencies. Your provider will interpret results in the context of your symptoms and medical history.

Short name

Eosinophil Count

Frequently asked questions

What causes eosinophils to be high?
High eosinophil counts can result from allergies, asthma, parasitic infections, certain cancers (like leukemia), or inflammatory conditions. Chronic conditions like rheumatoid arthritis or inflammatory bowel disease may also be linked to elevated eosinophils.
What does it mean if my eosinophil count is low?
Low eosinophil counts may occur with infections like tuberculosis, certain viral infections, or conditions affecting the bone marrow (e.g., aplastic anemia). It can also be a side effect of certain medications or autoimmune diseases.
Can I influence my eosinophil count?
While you can’t directly control eosinophil levels, managing allergies (e.g., avoiding triggers), treating infections promptly, and addressing chronic conditions (like asthma or inflammatory diseases) may help stabilize your count. Always follow your provider’s advice for managing underlying health concerns.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy