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Cerebrospinal Fluid (CSF) Ependymal Cell Count

Published: August 9, 2026Updated: August 16, 2026

This test measures the number of ependymal cells found in your cerebrospinal fluid (CSF). Ependymal cells are specialized cells lining the ventricles and central canal of the brain and spinal cord.

Quick summary

["Understanding your ependymal cell count can help assess potential issues in your brain’s fluid circulation or central nervous system health."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
51909-0
Short code
Ependymal cells NFr CSF
Synonyms
Ependymal cells NFr CSF
Category
chemistry
Sample
csf
Container
Sterile tube
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
1-2 mL
Stability
Immediate analysis required, Refrigerated: 1h
Hemolysis max
200
TAT
4–24 hours
Order
routine

Why This Test Might Be Ordered

Your healthcare provider may order this test if you have symptoms like headaches, nausea, or neurological concerns that could suggest abnormal fluid flow or blockages in the brain. It may also be used in cases of suspected tumors, infections, or other conditions affecting the CSF.

What to Expect During the Procedure

A small amount of CSF is collected through a procedure called a lumbar puncture (spinal tap). You’ll lie on your side and may feel mild pressure or discomfort during the needle insertion, but it’s usually brief. The test itself involves examining the fluid under a microscope to count ependymal cells.

Sample Collection and Preparation

The CSF sample is taken directly from your spinal column and sent to a lab for microscopic analysis. Ependymal cells are identified based on their unique shape and location within the fluid.

Interpreting Results

Results are typically reported as a count of ependymal cells per unit volume of CSF. Elevated counts might indicate conditions like hydrocephalus (fluid buildup) or other structural abnormalities in the brain’s ventricles.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance

Short name

CSF Ependymal Cells

Frequently asked questions

What Does an Abnormal Result Mean?
An abnormal ependymal cell count could signal issues such as blockages in the brain’s ventricular system, congenital abnormalities, or certain types of brain tumors. However, results alone aren’t diagnostic—they’re often used alongside other tests and symptoms to guide further evaluation.
How Often Should This Test Be Done?
This test is usually performed as part of a diagnostic evaluation rather than a routine screening. Your provider will determine if repeated testing is needed based on your symptoms and medical history.
Is There Any Risk or Side Effect?
The procedure carries minimal risk, but possible side effects include mild headache, bruising, or infection at the injection site. Follow your provider’s instructions for post-procedure care, such as staying hydrated or resting.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy