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Eosinophil count in serum/plasma (qualitative or semi-quantitative screening)

Published: August 9, 2026Updated: August 16, 2026

This test checks the presence or level of eosinophils, a type of white blood cell, in your blood. Eosinophils help fight infections and respond to allergies or inflammatory conditions.

Quick summary

["Eosinophil screening helps identify potential allergic reactions, infections, or inflammatory diseases."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
74354-2
Short code
Epi Cells NFr Spt
Synonyms
Epi Cells NFr Spt
Category
chemistry
Sample
sputum
Container
Sterile sputum container
Units
N/A
Ref low
0.8
Ref high
1.2
Critical range
— – 5 N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
85610
SNOMED
396252006
Specimen volume
3-5 mL
Stability
Room temperature: 2h, Refrigerated: 24h
TAT
4–24 hours
Order
routine

Why Might You Need This Test?

Your healthcare provider may order this test if you have symptoms like persistent itching, skin rashes, asthma, or unexplained allergies. It could also be used to monitor conditions like parasitic infections, certain cancers, or autoimmune disorders.

What Does the Test Involve?

A blood sample is taken, typically from your arm. The lab then examines the blood under a microscope to count eosinophils. The result may be qualitative (present or not) or semi-quantitative (approximate level).

What Are Common Causes of Elevated Eosinophils?

Elevated eosinophils can occur due to allergies, asthma, parasitic infections, certain cancers (like lymphoma or leukemia), inflammatory conditions, or reactions to medications.

What Are Common Causes of Normal or Low Eosinophils?

Eosinophils are usually low in cases of acute infections (like bacterial infections), severe stress, or during recovery from illness. They may also be low in certain genetic conditions or with certain medications.

Reference range

INR: 0.8-1.2 (warfarin: 2.0-3.0)N/A

Specimen: sputum

Inform your healthcare provider if you are taking blood thinners. No special preparation required.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Eosinophil counts can signal underlying conditions that require further investigation. High levels may prompt additional testing for allergies, infections, or autoimmune diseases. Low levels may not indicate a problem but could be part of a broader blood analysis for other conditions.

Short name

Eosinophil screening

Frequently asked questions

What does a high eosinophil count mean?
A high eosinophil count may suggest allergies, asthma, parasitic infections, or certain inflammatory or autoimmune conditions. Your doctor will discuss further tests or treatments based on your symptoms and results.
Results are typically available within 1 to 3 business days, depending on your lab. Your healthcare provider will contact you with the findings.
No special preparation is needed for this test. However, avoid taking blood-thinning medications (like aspirin) without consulting your doctor, as they may affect blood analysis results.
Is there any risk or discomfort with this test?
The test involves a small needle inserted into your arm, which may cause slight discomfort or bruising. Rarely, there could be a reaction to the needle or infection at the injection site, but these are minor risks.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy