Eosinophil count (serum/plasma, qualitative electrophoresis)

What Is Eosinophil Electrophoresis Used For?

Eosinophil electrophoresis is primarily used to qualitatively determine the presence and relative distribution of eosinophils in a blood sample. This method helps clinicians assess conditions where eosinophil counts may be elevated, such as allergic disorders, parasitic infections, or certain inflammatory diseases. It’s not typically used for precise quantitative measurements but can provide important qualitative insights.

How Is This Test Performed?

For this test, a small blood sample is drawn, and the serum or plasma is separated. The sample is then subjected to electrophoresis, a technique that separates blood cells based on their electrical charge. The presence of eosinophils is identified visually or through detection methods specific to these cells.

Common Conditions Evaluated With This Test

Eosinophil electrophoresis may be ordered to evaluate conditions where eosinophil levels are suspected to be abnormal, such as allergic reactions (e.g., asthma, eczema), parasitic infections, certain autoimmune diseases, or reactions to medications. It can also be part of a broader evaluation for unexplained symptoms like chronic fatigue or unexplained skin rashes.

What Does a Positive or Abnormal Result Mean?

An abnormal result indicating elevated eosinophils may suggest an underlying allergic or inflammatory process. However, this test alone does not provide a definitive diagnosis. Your healthcare provider will consider your symptoms, medical history, and other test results to determine the cause.