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Total Serum Immunoglobulin E (IgE) with Allergen-Specific IgE Profile (Screening Mix)

Published: August 9, 2026Updated: August 16, 2026

This test measures your body’s immune response to common allergens, including common airborne allergens, foods, and insect venom. It helps identify specific triggers for allergic reactions.

Quick summary

["Assess potential allergies and guide allergy management with targeted testing."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
15213-2
Short code
Epid Allerg Mix2 IgE Ql
Synonyms
Epid Allerg Mix2 IgE Ql
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
multidisk
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What This Test Measures

The test includes a general measurement of total IgE levels in your serum and specific IgE antibodies against a mix of common allergens. IgE is a type of antibody your immune system produces in response to allergens, which can cause allergic reactions like sneezing, itching, or skin rashes.

How the Test Works

Blood is drawn and processed to separate serum, which is then analyzed using immunoassay methods (likely fluorescence or chemiluminescence) to detect IgE levels and specific IgE responses to the included allergens. This helps pinpoint which allergens may be causing your symptoms.

Why It’s Done

Your healthcare provider may recommend this test if you have symptoms like sneezing, itching, skin reactions, or respiratory issues that suggest allergies. It’s also used to confirm allergies suspected through history or physical exam before planning treatment.

What to Expect Before the Test

No special preparation is needed. You may have a small needle inserted into your arm to draw blood, which usually takes a few minutes. Wear comfortable clothing and bring any medications you’re currently taking.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Elevated total IgE levels or specific IgE responses to allergens can indicate an allergic reaction risk. While these results don’t confirm a diagnosis alone, they help guide further testing or treatment plans, such as allergy shots or avoiding specific allergens. Results may also be used to monitor response to allergy management strategies.

Short name

IgE Screening Panel

Frequently asked questions

How long will I need to wait for results?
Results are typically available within 1 to 3 business days, depending on your lab’s processing schedule. Your healthcare provider will discuss the findings with you during your follow-up visit.
What does a positive result mean?
A positive result means your body has produced IgE antibodies against the tested allergens, which may suggest an allergic reaction risk. However, a positive result alone doesn’t confirm a diagnosis—it often prompts further testing or allergy evaluation by a specialist.
Can I avoid this test if I don’t have allergy symptoms?
Not necessarily. Even if you don’t have symptoms, this test can help identify potential allergens you may not realize affect you. Your healthcare provider may recommend it if they suspect allergies based on your medical history or other factors.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy