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Total IgE with Allergen-Specific IgE Profile (Serum)

Published: August 9, 2026Updated: August 16, 2026

This blood test measures your body’s immune response to specific allergens, including environmental triggers like pollen, dust mites, pet dander, or food substances.

Quick summary

["Helps identify potential allergies that may cause symptoms like sneezing, itching, or skin reactions."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
82047-2
Short code
Epid Allerg Mix2 IgE Qn
Synonyms
Epid Allerg Mix2 IgE Qn
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
multidisk
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What This Test Measures

Total IgE measures the overall level of Immunoglobulin E (IgE), a protein produced by your immune system in response to allergens. IgE is linked to allergic reactions. The test also includes specific IgE levels for common allergens (e.g., grass pollen, cat dander, peanuts), allowing doctors to pinpoint exact triggers.

Why It’s Done

Your doctor may recommend this test if you have symptoms like hives, asthma, eczema, or nasal congestion that suggest allergies. It helps determine whether allergens are causing your reactions and guides treatment plans like allergy shots or medication.

Sample Collection and Preparation

A blood sample is drawn from your arm, typically in a clinic or lab. The blood is processed to separate serum, which is then tested for IgE levels and allergen-specific antibodies.

What to Expect Before the Test

No special preparation is needed. You may eat and drink normally, but inform your doctor about any medications (especially blood thinners) or recent illnesses that could affect results.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

IgE Allergy Testing

Frequently asked questions

How long will results take?
Results are usually available within 1–3 business days, depending on lab processing times. Your doctor will discuss them with you during a follow-up visit.
Can I get results over the phone?
Some labs may provide results via secure patient portals or phone calls, but confirm with your doctor’s office for their specific communication methods.
Does this test cover all possible allergens?
No, this test includes a standard panel of common allergens. If your doctor suspects a less common allergen, they may order additional specific IgE tests or a broader panel.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy