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Allergen-Specific IgE, Serum — 73-Allergen Mix (RAST)

Published: August 9, 2026Updated: August 17, 2026

A blood test that measures IgE antibodies to multiple allergens in a 73-allergen panel, helping identify possible allergen sensitization.

Quick summary

["Results can show which allergens your immune system has reacted to, but they must be interpreted with your symptoms and medical history."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 17, 2026Editorial policy

Key facts at a glance

LOINC
24488-9
Short code
Epid Allerg Mix73 IgE RAST
Synonyms
Epid Allerg Mix73 IgE RAST
Category
liver
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Ref low
10
Ref high
40
Critical range
— – 500 N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
multidisk
CPT
84484
SNOMED
302774002
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What is this test?

This test measures allergen-specific IgE antibodies in your blood. RAST is a laboratory term for a type of allergen-specific IgE testing, and this version tests a mix of 73 allergens.

Why might I need this test?

You may need this test if you have symptoms such as sneezing, wheezing, hives, swelling, or digestive discomfort that may be related to an exposure to food, pollen, dust mites, animal dander, insects, or other substances.

How is the test performed?

A blood sample is collected and sent to a laboratory, where the laboratory measures IgE antibodies to the allergens included in the panel. The results are reported for the individual allergens tested.

How do I prepare for the test?

Fasting is usually not required. Tell your clinician about any medicines you take, recent allergen exposure, and worsening of asthma or other allergic symptoms, but do not stop prescribed medicines without medical advice.

Reference range

Adult: 10-40 U/LN/A

Specimen: serum

No special preparation required. Avoid fatty meals before the test if possible.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

A detectable or elevated result indicates sensitization to the particular allergen tested, meaning your immune system has produced IgE antibodies against it. A negative or undetectable result makes sensitization to that allergen less likely. These findings do not by themselves prove that a specific allergen causes your symptoms, so results should be interpreted alongside your history and, when appropriate, other allergy testing.

Short name

Allergen-Specific IgE (RAST)

Frequently asked questions

Does a positive result mean I am definitely allergic?
No. It indicates sensitization and must be compared with your symptoms, exposure history, and sometimes results from skin-prick testing or a supervised challenge.
Can this test identify the cause of my symptoms?
It can identify likely allergen targets, but several allergens may produce sensitization, and a sensitizing result may not be the true cause of your symptoms.
Is this the same as a skin-prick allergy test?
No. This test uses a blood sample to measure allergen-specific IgE, while skin-prick testing measures an immediate skin reaction after allergens are placed on the skin.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 17, 2026. · Read our editorial policy