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Epidermal Growth Factor Receptor (EGFR) Serological Screening Test

Published: August 9, 2026Updated: August 16, 2026

This test measures antibodies in your blood that may react to proteins related to epidermal growth factor receptor (EGFR), a protein involved in cell growth. It helps assess potential immune responses to EGFR-related conditions.

Quick summary

["This screening may support evaluation of certain cancers or autoimmune responses involving EGFR pathways."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
45382-9
Short code
Epidis Ab Ser Ql
Synonyms
Epidis Ab Ser Ql
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What This Test Measures

The test detects the presence of antibodies in your serum that could bind to EGFR or its related proteins. These antibodies are part of your immune system’s response and may be linked to conditions like certain cancers or autoimmune disorders.

Why It Might Be Ordered

Your healthcare provider may recommend this test if you have symptoms or a history suggestive of conditions where EGFR-related immune responses are suspected, such as certain cancers or inflammatory conditions.

Sample Collection and Preparation

A blood sample is drawn from a vein, typically in your arm. The serum portion is separated and sent to the lab for analysis using immunoassay methods to identify specific antibodies.

What to Expect Before the Test

No special preparation is needed, but you may be asked to avoid certain medications or foods that could interfere with results. Always follow your provider’s instructions.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Positive results may indicate an immune response to EGFR proteins, which could be relevant in diagnosing conditions like certain cancers (e.g., lung cancer in some genetic contexts) or autoimmune diseases. However, further testing and clinical correlation are required to interpret results accurately.

Short name

EGFR Antibody Screen (Serum)

Frequently asked questions

What does a positive result mean?
A positive result suggests the presence of antibodies against EGFR or related proteins, which may warrant additional testing or evaluation by your healthcare provider to explore underlying causes.
Could this test be affected by medications?
Some medications, particularly those targeting EGFR or immune-modulating drugs, may influence antibody levels. Your provider will discuss potential interactions with you before testing.
Is this test covered by insurance?
Coverage depends on medical necessity and your insurance plan. Check with your provider or insurance company to confirm if this test is included in your benefits.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy