Skip to content

Epinephrine (adrenaline) in plasma, mass concentration

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of epinephrine, a hormone produced by your adrenal glands, in your blood plasma. Epinephrine helps your body respond to stress or emergencies by increasing heart rate, blood pressure, and energy.

Quick summary

["Epinephrine helps your body react to stress; high levels may indicate medical conditions or recent events requiring medical evaluation."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
1462-1
Short code
Epineph 2h p 300 ug CLN PO Plas-mCnc
Synonyms
Epineph 2h p 300 ug CLN PO Plas-mCnc
Category
chemistry
Sample
plasma
Container
Lavender-top (EDTA) or Green-top (Heparin)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Might Be Ordered

Your healthcare provider may order this test to check for conditions affecting your adrenal glands, such as pheochromocytoma (a tumor that produces excess hormones) or adrenal insufficiency. It may also be used to monitor stress responses, diagnose certain heart conditions, or evaluate reactions to medications or trauma.

What to Expect Before the Test

No special preparation is usually needed. You may be asked to fast for a few hours before the test, but always follow your provider’s instructions. Bring any medications you’re taking, as they can affect results.

During the Test

A healthcare professional will draw blood from a vein in your arm. You may feel a slight pinch, but it usually doesn’t cause significant discomfort. The blood sample is then sent to a lab for analysis.

What the Results Mean

Results are compared to standard reference ranges, but exact values can vary by lab. High levels may signal conditions like pheochromocytoma or severe stress reactions, while very low levels could indicate adrenal gland issues or certain medications.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Epinephrine levels are critical for diagnosing adrenal gland tumors, evaluating hyperadrenergic states (e.g., from anxiety, trauma, or certain medications), or assessing autonomic dysfunction. Abnormal results often prompt further testing, such as imaging or additional hormone checks, to identify underlying causes.

Short name

Plasma Epinephrine Level

Frequently asked questions

How long does it take to get my results?
Results are typically available within 1–3 business days, depending on your lab’s processing time. Follow up with your healthcare provider to discuss your results and next steps.
What causes naturally high or low epinephrine levels?
High levels can occur from extreme stress, certain medications, or adrenal tumors. Low levels may result from adrenal gland disorders, medications, or chronic stress. Your provider will consider your full medical history and symptoms when interpreting results.
Can I take anything before or after the blood draw?
Avoid smoking or caffeine for 30 minutes before the draw, as they can temporarily affect epinephrine levels. Do not eat or drink anything (except water) for 8–12 hours before fasting tests, unless instructed otherwise. After the draw, resume your normal activities, but avoid strenuous exercise for a short time.
  1. 1
  2. 2
  3. 3

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy