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Epinephrine (Adrenaline) Mass Concentration in Plasma

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of epinephrine (adrenaline), a hormone produced by your adrenal glands, in your blood plasma. Epinephrine helps regulate your body’s response to stress, heart rate, and blood pressure.

Quick summary

["Epinephrine helps your body respond to stress by increasing heart rate and blood pressure."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
47137-5
Short code
Epineph 2h p 300 ug CLN PO Plas-sCnc
Synonyms
Epineph 2h p 300 ug CLN PO Plas-sCnc
Category
chemistry
Sample
plasma
Container
Lavender-top (EDTA) or Green-top (Heparin)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why Is This Test Done?

Your doctor may order this test to check for conditions affecting your adrenal glands, such as pheochromocytoma (a tumor that produces too much adrenaline), adrenal insufficiency, or to monitor symptoms like high blood pressure, rapid heartbeat, or severe stress reactions.

What to Expect Before the Test

No special preparation is needed. You may have a small needle inserted into a vein in your arm, and blood will be drawn. This is usually done in a doctor’s office or lab.

What the Results Mean

Higher-than-normal levels may suggest conditions like pheochromocytoma or severe stress responses. Lower-than-normal levels might indicate adrenal gland issues. Your doctor will interpret results in relation to your symptoms and medical history.

Common Conditions Monitored

This test helps diagnose or manage conditions linked to abnormal adrenaline production, such as adrenal tumors, certain heart conditions, or chronic stress disorders.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Epinephrine levels can be elevated in emergencies like severe allergic reactions (anaphylaxis), trauma, or extreme stress. Chronic high levels may cause long-term health risks like high blood pressure or heart strain. Low levels can signal adrenal gland dysfunction or other hormonal imbalances.

Short name

Epinephrine Level

Frequently asked questions

Why might my doctor ask for this test?
Your doctor may recommend this test if you have symptoms like unexplained high blood pressure, rapid heartbeat, sweating, or anxiety that don’t go away with usual treatments. It’s also used to check for adrenal gland tumors or other conditions affecting hormone production.
What does a high epinephrine level usually mean?
A high epinephrine level often points to conditions like pheochromocytoma (a tumor in your adrenal glands), severe stress reactions, or certain heart or blood pressure disorders. Your doctor will review your symptoms and other test results to determine the cause.
Can diet or lifestyle affect this test?
Diet or lifestyle changes may not directly impact epinephrine levels, but stress, exercise, or certain medications (like stimulants) can temporarily raise them. Avoid caffeine or stress before the test if advised by your doctor.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy