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Erythropoietin (EPO) concentration, serum/plasma

Published: August 9, 2026Updated: August 16, 2026

This test measures the level of erythropoietin (EPO), a hormone produced by the kidneys that helps stimulate red blood cell production in your bone marrow.

Quick summary

["EPO helps your body produce healthy red blood cells; low levels may indicate kidney issues or anemia."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
23635-6
Short code
EPO Gvn Dose-aCnt
Synonyms
EPO Gvn Dose-aCnt
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Might Be Ordered

Your doctor may recommend this test if you have symptoms like fatigue, shortness of breath, or pale skin, which could suggest anemia. It may also be used to monitor kidney function or evaluate responses to treatments like chemotherapy or hormone therapy.

What to Expect Before the Test

No special preparation is usually needed, but you may be asked to fast for a few hours before the blood draw if instructed by your healthcare provider. Bring any medications you’re currently taking to your appointment.

What the Test Involves

A healthcare professional will draw blood from a vein in your arm. The sample is sent to a lab where it is analyzed to measure EPO levels. The process typically takes a few minutes.

What the Results Mean

Results are interpreted by your doctor based on your overall health, symptoms, and medical history. Abnormal levels may signal conditions like kidney disease, anemia, or certain cancers.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

EPO plays a critical role in maintaining red blood cell production. Low levels may indicate kidney problems, which can impair red blood cell formation. High levels can sometimes be linked to conditions like polycythemia (overproduction of red blood cells) or certain cancers, though further evaluation is needed to confirm.

Short name

EPO Level

Frequently asked questions

How long does it take to get my EPO test results?
Results are usually available within 1 to 3 business days, depending on your lab and healthcare provider. Your doctor will contact you once they are ready to discuss the findings.
What causes low EPO levels?
Low EPO levels can result from chronic kidney disease, anemia, or conditions that affect kidney function. Certain medications or treatments, such as chemotherapy, may also influence EPO production.
Can EPO levels be affected by diet or supplements?
Dietary factors like iron, vitamin B12, and folate can indirectly support red blood cell health, but they do not directly affect EPO levels. Always follow your doctor’s advice regarding supplements or dietary changes.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy