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Fluorimetric Intensity Measurement of BRCA-Associated Mutations in Plasma

Published: August 9, 2026Updated: August 16, 2026

This test measures the presence of genetic mutations linked to an increased risk of breast and ovarian cancer in a blood sample. It helps determine if you may benefit from additional screening or preventive measures.

Quick summary

["This test assesses your genetic risk for certain cancers by detecting specific mutations in your DNA."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
85310-1
Short code
ER fluor intensity Br ca spec Ql ImStn
Synonyms
ER fluor intensity Br ca spec Ql ImStn
Category
coagulation
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
immune-stain
CPT
86430
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Might Be Ordered

Your healthcare provider may recommend this test if you have a family history of breast or ovarian cancer, or if you are at high risk due to other factors like age or specific genetic syndromes. It’s also used in certain screening programs for people with a personal or family history of these cancers.

What to Expect Before the Test

No special preparation is needed for this blood test. You may have a small needle inserted into your arm to draw a blood sample, similar to other routine blood tests. The process usually takes a few minutes.

What Happens During the Test

The blood sample is analyzed using a specialized technique that detects mutations in the BRCA genes. This involves examining the DNA for specific changes that may increase cancer risk. The results are compared to known genetic profiles to identify mutations.

What the Results Mean

Results can be categorized as negative (no mutations detected), positive (mutations found), or uncertain. A positive result means you may have a higher risk of breast or ovarian cancer and may need further testing or monitoring. A negative result suggests no mutations were found in this test.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

This test is critical for identifying individuals at higher risk for hereditary breast and ovarian cancer. Early detection allows for proactive management, such as increased surveillance, risk-reducing surgeries, or chemoprevention strategies. It helps guide personalized cancer prevention plans tailored to your genetic profile.

Short name

BRCA Mutation Screening (Fluorimetric)

Frequently asked questions

What does a positive result mean for my health?
A positive result indicates the presence of BRCA mutations linked to increased cancer risk. This doesn’t mean you will definitely get cancer, but it means you are at higher risk and may need closer monitoring, additional genetic counseling, or preventive options like surgery or medication.
Will this test affect my insurance coverage or future medical care?
Results from this test may influence your healthcare decisions and could impact insurance coverage for related screenings or treatments. Always discuss the implications with your healthcare provider and insurance company to understand how the results may affect your care plan.
Can I get this test if I don’t have a family history of cancer?
Yes, this test can be recommended for individuals who are at average risk but have certain risk factors, such as age, lifestyle, or other genetic markers. It’s also sometimes offered as part of broader genetic screening programs, even without a family history.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy