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Hemoglobin A1c (HbA1c) with 24-hour urine collection for specific protein analysis (e.g., microalbuminuria)

Published: August 9, 2026Updated: August 16, 2026

This test measures certain proteins in your urine over 24 hours, often used to assess kidney function or detect small protein leaks that may signal underlying conditions like diabetes or kidney disease.

Quick summary

["This test helps track kidney health and protein loss in urine over time."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
86724-2
Short code
E rhusiopathiae Spec Ql Cult
Synonyms
E rhusiopathiae Spec Ql Cult
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
organism-specific-culture
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What This Test Measures

The test involves collecting all urine produced in a 24-hour period and analyzing it for specific proteins, such as albumin or microalbumin. These proteins can indicate whether your kidneys are functioning normally or if there is an abnormal amount being lost in urine, which may signal conditions like diabetic nephropathy or early kidney disease.

Why It Matters in Your Health

Detecting protein in urine early can help doctors monitor kidney health, especially in people with diabetes, high blood pressure, or a family history of kidney disease. It may also help identify other conditions affecting protein metabolism.

How the Test Works

Your urine sample is collected in a container over 24 hours. The lab processes the sample to measure protein levels, often using sensitive methods like immunoassay or nephelometry to detect even small amounts.

What to Expect Before the Test

No special preparation is needed beyond collecting all urine in a container for the full 24-hour period. Drink enough water to produce urine throughout the day, but avoid excessive diuretics or medications that might affect urine protein levels unless instructed otherwise.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Elevated protein levels in urine can indicate kidney damage, inflammation, or other systemic conditions. While some protein loss is normal, persistent or high levels may require further evaluation to prevent complications like kidney failure or cardiovascular risks. This test is particularly useful in monitoring chronic diseases like diabetes or hypertension.

Frequently asked questions

Why might my doctor order this test?
Your doctor may recommend this test if you have diabetes, high blood pressure, a history of kidney problems, or symptoms like swelling, frequent urination, or fatigue. It helps track kidney function and identify early signs of protein loss that could affect your health over time.
What does a normal result mean?
A normal result means your urine typically contains minimal protein, suggesting your kidneys are functioning well. However, even a single test may not be definitive, so follow-up tests or monitoring may be needed if you have risk factors for kidney disease.
Can diet or medications affect this test?
Yes, certain foods (like high-sodium or high-protein diets), medications (such as NSAIDs or some blood pressure drugs), or even stress can temporarily affect urine protein levels. Your doctor may advise adjustments to your diet or medications before the test if needed.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy