DNA from the stratum corneum (skin surface layer) analyzed via probe-based assay
This test measures genetic material collected from the outer layer of your skin to assess potential genetic markers or mutations.
["Understanding your skin’s DNA may help identify risks for certain inherited conditions or skin-related health concerns."]
Key facts at a glance
- LOINC
- 72505-1
- Short code
- E rostratum DNA Spec Ql NAA+probe
- Synonyms
- E rostratum DNA Spec Ql NAA+probe
- Category
- chemistry
- Sample
- serum
- Container
- Red-top tube (SST)
- Units
- N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Method
- probe-amp-tar
- Specimen volume
- 5 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
- Hemolysis max
- 500
- Lipemia max
- 1000
- Icterus max
- 500
- TAT
- 4–24 hours
- Order
- routine
What This Test Measures
The test collects cells from the stratum corneum—the outermost layer of your skin—using a gentle swab or pad. DNA from these cells is then analyzed to detect specific genetic sequences or mutations, often using a specialized probe-based technique. This method can help identify genetic variations that may relate to inherited conditions or skin health.
Why It’s Done
Your healthcare provider may recommend this test if you have a family history of genetic skin disorders, certain cancers (like melanoma), or if you’re undergoing research involving skin-related genetic studies. It can also be part of a broader genetic screening process.
Sample Collection Process
A healthcare professional will gently apply a swab or pad to your skin to collect cells from the stratum corneum. The sample is then processed in a lab to extract and analyze the DNA. This process is painless and typically takes a few minutes.
What to Expect After Testing
After your sample is collected, it is sent to a lab for analysis. Results may take several days to weeks, depending on the complexity of the testing. You’ll receive a detailed report from your healthcare provider explaining the findings.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
Clinical Significance
Frequently asked questions
This test is primarily used for research or specific genetic screening purposes. It may help identify inherited conditions that could affect your skin or overall health, allowing for early monitoring or preventive measures. However, it is not a routine diagnostic test for most medical conditions.
How long does it take to get results from this test?
Is this test painful or uncomfortable?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy