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Red Blood Cell Distribution Width in Fetal Blood (Autoanalyzer Method)

Published: August 9, 2026Updated: August 17, 2026

This test measures the variation in size of red blood cells (RBCs) in fetal blood, which can help assess potential blood-related conditions in the fetus.

Quick summary

["Measuring RBC size variation may support prenatal health evaluations."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 17, 2026Editorial policy

Key facts at a glance

LOINC
62247-2
Short code
Erythrocyte DistWidth Bld Fetus Auto
Synonyms
Erythrocyte DistWidth Bld Fetus Auto
Category
chemistry
Sample
whole-blood
Container
Lavender-top (EDTA)
Units
N/A
Ref low
4.2
Ref high
5.9
Critical range
2 N/A – 7 N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
automated-count
CPT
85041
Specimen volume
3 mL
Stability
Room temperature: 4h, Refrigerated: 24h
Hemolysis max
0
Lipemia max
0
Icterus max
0
TAT
4–24 hours
Order
routine

Why Is This Test Done?

Your healthcare provider may order this test if there are concerns about fetal anemia, blood flow issues, or genetic conditions that could affect red blood cell production or size. It may also be part of routine prenatal monitoring in certain cases.

What Does the Test Involve?

A small blood sample is taken from the fetus, often through procedures like a cordocentesis or amniocentesis. The sample is analyzed to determine the range of RBC sizes, which is then reported as the red blood cell distribution width (RDW).

What Do Results Mean?

The results provide a measure of RBC size variability, which can indicate whether RBCs are consistently produced or if there is an underlying issue affecting their development. Abnormal results may signal conditions requiring further investigation.

What Are Common Causes of Abnormal Results?

Elevated RDW in fetal blood could be linked to conditions like fetal anemia, thalassemia, or other genetic disorders affecting RBC production. Lower-than-expected RDW might suggest normal RBC uniformity or specific genetic factors.

Reference range

Adult males: 4.2-5.9; Females: 3.8-5.1 x 10^12/LN/A

Specimen: whole-blood

No special preparation usually required. Stay well hydrated. Inform your healthcare provider of all medications and supplements you are taking.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

RDW-Fet

Frequently asked questions

Why might my healthcare provider recommend this test during pregnancy?
Your provider may recommend it if you have a history of conditions like thalassemia, sickle cell disease, or other genetic blood disorders in your family, or if you are at higher risk for complications. It helps ensure the health of your baby’s blood cells.
How is the blood sample collected for this test?
The sample is taken through a specialized procedure, such as a cordocentesis (direct blood draw from the umbilical cord) or amniocentesis (fluid sample from the amniotic sac). This is done under careful medical supervision to ensure safety.
What are the typical follow-up steps if my RDW result is abnormal?
If results are abnormal, your healthcare provider may recommend additional testing, such as genetic counseling, further blood studies, or monitoring for specific fetal conditions. They will discuss next steps with you based on your individual situation.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 17, 2026. · Read our editorial policy