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Red Blood Cell Sedimentation Rate (Erythrocyte Sedimentation Rate)

Published: August 9, 2026Updated: August 17, 2026

This test measures how quickly red blood cells settle in a sample of blood over time. It can help identify inflammation or infection in your body.

Quick summary

["ESR helps doctors check for conditions like infections, autoimmune diseases, or other inflammatory processes."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 17, 2026Editorial policy

Key facts at a glance

LOINC
43402-7
Short code
Erythrocyte Sed Rat Bld 15M
Synonyms
Erythrocyte Sed Rat Bld 15M
Category
chemistry
Sample
whole-blood
Container
Lavender-top (EDTA)
Units
N/A
Ref low
4.2
Ref high
5.9
Critical range
2 N/A – 7 N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
m-reading
CPT
85041
Specimen volume
3 mL
Stability
Room temperature: 4h, Refrigerated: 24h
Hemolysis max
0
Lipemia max
0
Icterus max
0
TAT
4–24 hours
Order
routine

Why Is This Test Done?

Your doctor may order an ESR to monitor conditions such as rheumatoid arthritis, lupus, or other inflammatory diseases. It can also be used to check for infections or to evaluate how your body is responding to treatment.

How Is the Test Performed?

A small amount of your blood is drawn from a vein, typically in your arm. The blood is placed in a special tube and allowed to sit undisturbed for a set period. The rate at which red blood cells settle at the bottom of the tube is measured.

What Does the Result Mean?

The ESR result is not a specific number but a rate (often expressed in millimeters per hour). Higher rates may indicate inflammation, while lower rates may suggest no active inflammation. Your doctor will interpret the result in the context of your overall health and symptoms.

Common Conditions Monitored

ESR is commonly used to track conditions like autoimmune diseases (e.g., rheumatoid arthritis, lupus), infections, and other inflammatory disorders. It can also be part of routine check-ups for certain chronic conditions.

Reference range

Adult males: 4.2-5.9; Females: 3.8-5.1 x 10^12/LN/A

Specimen: whole-blood

No special preparation usually required. Stay well hydrated. Inform your healthcare provider of all medications and supplements you are taking.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance: ESR is a non-specific marker of inflammation. While it can suggest the presence of inflammation, it does not pinpoint the exact cause. Doctors often use it alongside other tests and clinical findings to guide diagnosis and treatment decisions.

Short name

ESR

Frequently asked questions

Why might my ESR be higher than usual?
Your ESR may be elevated due to infections, autoimmune diseases, certain cancers, or other inflammatory conditions. Stress, pregnancy, or certain medications can also temporarily affect it. Always discuss your results with your healthcare provider.
How often should I get this test?
Your doctor will determine how often you need this test based on your health condition and treatment plan. Regular monitoring may be necessary for chronic inflammatory diseases or ongoing health management.
Can lifestyle changes affect my ESR?
Yes, lifestyle factors like diet, exercise, and managing stress can influence inflammation levels. While ESR itself doesn’t directly reflect lifestyle, maintaining a healthy lifestyle may support overall health and help manage conditions that affect ESR.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 17, 2026. · Read our editorial policy