ESBL Detection by Phenotypic Screening (e.g., Modified Hodge Test or Disk Diffusion)

What This Test Measures

ESBL is an enzyme produced by some bacteria that can break down certain antibiotics, such as penicillin and cephalosporins. This test detects bacteria that produce ESBL, which can lead to harder-to-treat infections. The test uses a specific method to identify these bacteria in a blood or urine sample.

Why It’s Done

Your healthcare provider may order this test if you have symptoms of an infection (like fever, pain, or drainage) and are being treated with antibiotics that might be affected by ESBL. It helps determine if the bacteria causing your infection are resistant to common antibiotics, guiding treatment decisions.

Sample Collection

A blood or urine sample is collected for testing. Blood samples are typically drawn from a vein in your arm, while urine samples are collected in a clean container. The sample is then sent to a lab for analysis.

Test Process

The test involves growing bacteria from your sample on a special medium and exposing it to specific antibiotics. If ESBL-producing bacteria are present, they may grow differently or show resistance patterns that indicate ESBL production. Results are interpreted by a healthcare professional.