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Extended-Spectrum Beta-Lactamase (ESBL) Detection in Bacteria by Gene Identification (Qualitative)

Published: August 9, 2026Updated: August 16, 2026

This test checks if certain genes are present in bacteria that may make them resistant to common antibiotics like penicillin and cephalosporins.

Quick summary

["Helps doctors determine if your infection could be harder to treat with standard antibiotics."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
98064-9
Short code
ESBL blaCTX-M-14 gene Islt/Spm Ql
Synonyms
ESBL blaCTX-M-14 gene Islt/Spm Ql
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
molgen
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Matters for Your Health

ESBL-producing bacteria can spread infections that are more difficult to cure with typical antibiotics. This test helps healthcare providers choose the best treatment for your specific infection.

What to Expect Before the Test

No special preparation is needed for this test. A sample of your bodily fluid (like blood, urine, or other bodily secretions) will be collected and sent to a lab for analysis. The lab will look for specific genetic markers associated with ESBL production.

What the Results Mean

If the test is positive, it means your bacteria may produce ESBL enzymes, which can break down certain antibiotics. This doesn’t mean you have an infection yet, but it helps guide treatment choices. If negative, your bacteria are less likely to produce ESBL.

Common Situations Where This Test Is Used

This test is often used in patients with infections that don’t respond well to standard antibiotics, or when doctors suspect the presence of ESBL-producing bacteria, such as in urinary tract infections, bloodstream infections, or wound infections.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

ESBL-producing bacteria can lead to more severe infections that are harder to treat. Early identification allows healthcare providers to switch to more effective antibiotics, reducing the risk of prolonged illness and antibiotic resistance in your body or the community. It also helps prevent the spread of resistant bacteria to others.

Short name

ESBL Gene Screening

Frequently asked questions

What does a positive result mean for my treatment?
A positive result indicates that your bacteria may produce ESBL enzymes, which can make certain antibiotics less effective. Your healthcare provider will discuss alternative antibiotics or treatments that are more likely to work against these bacteria.
Can I still take antibiotics if this test is positive?
Not necessarily. If the test is positive, your doctor may recommend different antibiotics that target bacteria producing ESBL. It’s important to follow their advice to ensure the infection is treated effectively and to prevent antibiotic resistance.
How long does it take to get the results of this test?
Results can typically be available within a few days, depending on the lab’s processing time. Your healthcare provider will contact you once the results are ready.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy