Extended-spectrum β-lactamase (ESBL) detection in bacterial isolates via gene sequencing (qualitative)
This test checks if bacteria in your sample carry genes that make them resistant to certain antibiotics, including extended-spectrum penicillin drugs.
["Determines antibiotic resistance patterns to guide treatment choices."]
Key facts at a glance
- LOINC
- 98063-1
- Short code
- ESBL blaCTX-M-15 gene Islt/Spm Ql
- Synonyms
- ESBL blaCTX-M-15 gene Islt/Spm Ql
- Category
- chemistry
- Sample
- serum
- Container
- Red-top tube (SST)
- Units
- N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Method
- molgen
- Specimen volume
- 5 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
- Hemolysis max
- 500
- Lipemia max
- 1000
- Icterus max
- 500
- TAT
- 4–24 hours
- Order
- routine
Why This Test Is Done
Your healthcare provider may order this test if you’ve been treated with antibiotics and symptoms persist, or if you’ve been exposed to bacteria known to produce ESBL. It helps identify infections caused by bacteria resistant to common antibiotics, ensuring more effective treatment options.
How the Test Works
A small sample of bacteria is taken from your body (e.g., blood, urine, or wound) and analyzed for specific genes (ESBL genes) using advanced sequencing technology. This confirms whether the bacteria carry resistance markers.
Sample Collection and Preparation
You’ll likely provide a sample (e.g., blood draw, urine collection, or swab) during a routine visit. The lab processes the sample to isolate bacteria, then tests for the ESBL gene using genetic sequencing.
What to Expect After the Test
Results are typically ready within 2–5 business days. Your provider will discuss findings and recommend next steps, such as adjusting antibiotic therapy if needed.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
Clinical Significance
Short name
ESBL Gene Screening (Qualitative)
Frequently asked questions
This test is critical for managing infections caused by bacteria like *E. coli* or *Klebsiella*, which can spread in hospitals or communities. Detecting ESBL helps prevent unnecessary antibiotic use and reduces resistance risks.
How does this test differ from a routine urine or blood culture?
What if my test comes back positive for ESBL?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy