Beta-lactamase gene sequencing (qualitative, confirmatory)
This test checks whether certain bacteria produce beta-lactamase enzymes that make them resistant to common antibiotics like penicillin and cephalosporins. It helps doctors determine the best treatment for infections caused by these resistant bacteria.
["Helps identify antibiotic-resistant bacteria to guide infection treatment."]
Key facts at a glance
- LOINC
- 85839-9
- Short code
- ESBL blaTEM gene Islt/Spm Ql
- Synonyms
- ESBL blaTEM gene Islt/Spm Ql
- Category
- chemistry
- Sample
- serum
- Container
- Red-top tube (SST)
- Units
- N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Method
- molgen
- Specimen volume
- 5 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
- Hemolysis max
- 500
- Lipemia max
- 1000
- Icterus max
- 500
- TAT
- 4–24 hours
- Order
- routine
Why This Test Matters for Your Health
Beta-lactamase enzymes can make antibiotics less effective, leading to harder-to-treat infections. This test confirms if bacteria in your sample carry genes that produce these enzymes, helping doctors choose the right antibiotics for your condition.
How the Test Works
A small sample of your blood, urine, or other bodily fluid is tested for specific genetic markers linked to beta-lactamase production. The test uses advanced molecular techniques to detect these genes, ensuring accurate identification of resistant bacteria.
Common Uses and When You Might Need It
This test is typically ordered if you have an infection that doesn’t improve with standard antibiotics, or if you’re at higher risk for antibiotic-resistant infections (e.g., hospital-acquired infections, certain chronic illnesses). It’s also used in research or monitoring to track antibiotic resistance trends.
What to Expect Before the Test
No special preparation is usually needed. Your healthcare provider will collect a sample (e.g., blood, urine, or swab) during a routine visit. The sample may be sent to a lab for processing, and results are typically ready within a few days to a week, depending on the lab.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
Positive results indicate bacteria resistant to beta-lactam antibiotics, which may require alternative treatments like carbapenems, colistin, or other non-beta-lactam antibiotics. Early identification helps prevent unnecessary antibiotic use, reduces treatment failures, and lowers the risk of spreading antibiotic-resistant infections in healthcare settings.
Short name
ESBL Gene Confirmation
Frequently asked questions
What does a positive result mean?
Can I take antibiotics before this test?
How long will it take to get the results?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy