Estradiol (serum/plasma) mass concentration
This test measures the amount of estradiol, a primary female sex hormone, in your blood. Estradiol plays a key role in reproductive health, bone density, and overall well-being.
["Estradiol helps regulate menstrual cycles, supports fertility, and maintains bone health."]
Key facts at a glance
- LOINC
- 58854-1
- Short code
- Estradiol 4D p chal SerPl-mCnc
- Synonyms
- Estradiol 4D p chal SerPl-mCnc
- Category
- chemistry
- Sample
- serum
- Container
- Red-top tube (SST)
- Units
- N/A
- Ref low
- 20
- Ref high
- 400
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- CPT
- 82670
- SNOMED
- 300919004
- Specimen volume
- 5 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
- Hemolysis max
- 500
- Lipemia max
- 1000
- Icterus max
- 500
- TAT
- 4–24 hours
- Order
- routine
Why This Test Might Be Ordered
Your healthcare provider may recommend this test to evaluate hormonal balance, diagnose conditions related to hormone imbalances, or monitor treatment for conditions like polycystic ovary syndrome (PCOS), menopause, or hormone therapy.
What to Expect Before the Test
No special preparation is typically needed, but you may be asked to fast for 8–12 hours before the blood draw if your test involves a fasting sample. Wear comfortable clothing and plan to stay for about 15 minutes while blood is drawn.
What Happens During the Test
A healthcare professional will insert a small needle into a vein in your arm. You may feel a slight pinch, but the procedure is quick. Blood will be collected into a tube, and you can resume normal activities immediately.
What the Results Mean
Results are interpreted by your provider based on your age, sex, medical history, and symptoms. High or low levels may indicate conditions like ovarian tumors, thyroid disorders, or hormonal imbalances that require further evaluation.
Reference range
Premenopausal: 20-400 pg/mL; Postmenopausal: <30 pg/mLN/A
For females: inform if menstrual cycle status. For certain tests, timing within menstrual cycle may matter.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
Estradiol levels are critical for diagnosing hormonal disorders, assessing fertility, evaluating menopausal symptoms, or monitoring hormone replacement therapy. Abnormal results may prompt additional testing, such as follicle-stimulating hormone (FSH) or luteinizing hormone (LH) levels, to better understand the underlying cause.
Short name
Estradiol Level
Frequently asked questions
What does an elevated estradiol level mean?
How long does it take to get results?
Can lifestyle changes affect estradiol levels?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy