Estrogen (estradiol) in serum/plasma, measured as mass concentration via immunoassay
This test measures the amount of estradiol, a key female sex hormone, in your blood. Estradiol helps regulate menstrual cycles, supports reproductive health, and influences bone density and metabolism.
["Estradiol levels can help diagnose hormonal imbalances or track treatment effectiveness for conditions like menopause or fertility issues."]
Key facts at a glance
- LOINC
- 97741-3
- Short code
- Estradiol Aspirate-sCnc
- Synonyms
- Estradiol Aspirate-sCnc
- Category
- chemistry
- Sample
- serum
- Container
- Red-top tube (SST)
- Units
- N/A
- Ref low
- 20
- Ref high
- 400
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- CPT
- 82670
- SNOMED
- 300919004
- Specimen volume
- 5 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
- Hemolysis max
- 500
- Lipemia max
- 1000
- Icterus max
- 500
- TAT
- 4–24 hours
- Order
- routine
Why This Test Might Be Ordered
Your healthcare provider may recommend this test if you have symptoms like irregular periods, hot flashes, low libido, or if you’re undergoing treatment for conditions like polycystic ovary syndrome (PCOS), endometriosis, or hormone replacement therapy. It may also be checked during fertility evaluations or to monitor hormone-related cancers.
What to Expect Before the Test
No special preparation is usually needed, but you may be asked to fast for 8–12 hours before the draw if your lab uses a fasting protocol. Wear comfortable clothing and plan to sit still for a few minutes while blood is drawn.
What the Test Results Mean
Results are compared to standard ranges for your age, sex, and health status. Low levels might indicate hormonal deficiencies, while high levels could signal conditions like ovarian tumors or Cushing’s syndrome. Your provider will interpret results in the context of your overall health.
Common Reasons for Abnormal Results
Elevated estradiol levels may be linked to tumors, hormonal medications, or conditions like thyroid disorders. Low levels could result from menopause, pituitary issues, or certain medications. Always discuss any concerns with your doctor.
Reference range
Premenopausal: 20-400 pg/mL; Postmenopausal: <30 pg/mLN/A
For females: inform if menstrual cycle status. For certain tests, timing within menstrual cycle may matter.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
◆Associated findings1
Short name
Estradiol Level
Frequently asked questions
How long does it take to get my estradiol test results back?
Can I take anything before my estradiol test?
What should I do if my estradiol levels are outside the normal range?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy