Estradiol (Serum/Plasma) by Immunoassay
This test measures the amount of estradiol, a primary female sex hormone, in your blood. It helps assess hormone balance, reproductive health, and potential hormonal disorders.
["Estradiol levels can influence fertility, bone health, and other hormonal functions."]
Key facts at a glance
- LOINC
- 51498-4
- Short code
- Estradiol sp3 p chal SerPl-mCnc
- Synonyms
- Estradiol sp3 p chal SerPl-mCnc
- Category
- chemistry
- Sample
- serum
- Container
- Red-top tube (SST)
- Units
- N/A
- Ref low
- 20
- Ref high
- 400
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- CPT
- 82670
- SNOMED
- 300919004
- Specimen volume
- 5 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
- Hemolysis max
- 500
- Lipemia max
- 1000
- Icterus max
- 500
- TAT
- 4–24 hours
- Order
- routine
Why This Test Might Be Ordered
Your healthcare provider may recommend this test to evaluate symptoms like irregular menstrual cycles, menopause-related changes, or to monitor hormone therapy. It can also be used during pregnancy or to check for conditions like polycystic ovary syndrome (PCOS).
What to Expect Before the Test
No special preparation is usually needed, but you may be asked to fast for 8–12 hours before the draw if your lab requires it. Wear comfortable clothing and plan to stay near the testing site for a short time.
What Happens During the Test
A healthcare professional will draw blood from a vein in your arm. You may feel a slight pinch, but the procedure is quick. The blood sample is then sent to a lab for analysis using an immunoassay method to detect estradiol levels.
What the Results Mean
Results are typically reported in picograms per milliliter (pg/mL) or other standardized units. Your provider will interpret the results in relation to your age, health, and symptoms. Abnormal levels may signal hormonal imbalances or other health concerns.
Reference range
Premenopausal: 20-400 pg/mL; Postmenopausal: <30 pg/mLN/A
For females: inform if menstrual cycle status. For certain tests, timing within menstrual cycle may matter.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
Estradiol levels can indicate reproductive health, fertility status, and risks for conditions like osteoporosis or breast cancer. Low levels may suggest menopause, thyroid issues, or pituitary disorders, while high levels could signal tumors or other hormonal imbalances. Always discuss results with your provider.
Short name
Estradiol Level
Frequently asked questions
How long does it take to get my estradiol test results?
Can I take anything for my estradiol test?
What if my estradiol level is outside the normal range?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy