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Estrogen [Mass/time] in 24-Hour Urine

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of estrogen hormones excreted in urine collected over 24 hours. It can help assess estrogen production and changes in hormone levels over time.

Quick summary

["The result reflects estrogen excretion during the 24-hour urine collection and is interpreted alongside the collection quality and your clinical situation."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
25402-9
Short code
Estrogen 24h Ur-sRate
Synonyms
Estrogen 24h Ur-sRate
Category
chemistry
Sample
urine
Container
Sterile urine container
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
10 mL
Stability
Room temperature: 2h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
0
Lipemia max
0
Icterus max
0
TAT
4–24 hours
Order
routine

What the Test Measures

Estrogens are a group of hormones, including estradiol, estriol, and estrone. This test measures the total amount of estrogen released in the urine over a full day.

How the Test Is Collected

Urine is collected for 24 hours, usually into a labeled container provided by the laboratory or clinic. The collection should follow the specific instructions given by the healthcare provider, including how and when the container is stored or returned.

Why It May Be Ordered

A 24-hour urine estrogen test may be used to evaluate hormone production, investigate menstrual or fertility concerns, or monitor certain conditions and treatments affecting estrogen levels.

Factors That May Affect Results

Results can be influenced by incomplete urine collections, missed or spilled samples, medications, supplements, menstrual status, pregnancy, and changes in hormone production. The laboratory may request additional information to help interpret the result.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

24-Hour Urine Estrogen

Frequently asked questions

Why is a 24-hour urine collection needed?
Collecting urine for the full 24 hours provides a more complete measure of how much estrogen your body is producing and releasing than a single urine sample.
What happens if part of the urine collection is missed?
A missed or incomplete collection can make the result inaccurate or difficult to interpret. Ask the laboratory or clinic whether the test should be repeated.
Does this test diagnose infertility?
No. It may be one part of an evaluation for fertility or hormonal concerns, but infertility can have many causes and is usually assessed using several tests and clinical information.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy