Estrogen, Serum or Plasma Mass Concentration (Calculated)
This test measures the amount of estrogen, a key female sex hormone, in your blood. Estrogen helps regulate menstrual cycles, supports reproductive health, and affects bone density and cholesterol levels.
["Estrogen levels can help diagnose hormonal imbalances or track conditions like menopause or fertility issues."]
Key facts at a glance
- LOINC
- 53765-4
- Short code
- Estrogen SerPl Calc-mCnc
- Synonyms
- Estrogen SerPl Calc-mCnc
- Category
- chemistry
- Sample
- serum
- Container
- Red-top tube (SST)
- Units
- N/A
- Ref low
- 0
- Ref high
- 17
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Method
- calculated
- Specimen volume
- 5 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
- Hemolysis max
- 500
- Lipemia max
- 1000
- Icterus max
- 500
- TAT
- 4–24 hours
- Order
- routine
Why This Test Might Be Ordered
Your healthcare provider may recommend this test if you have symptoms like irregular periods, hot flashes, or signs of hormonal disorders. It could also be used to monitor conditions like polycystic ovary syndrome (PCOS), breast cancer, or to check hormone replacement therapy effectiveness.
What to Expect Before the Test
No special preparation is usually needed, but you may be asked to fast for 8–12 hours before the blood draw if your lab requires it. Wear a comfortable shirt for easy access to your arm.
What Happens During the Test
A healthcare professional will insert a small needle into a vein in your arm to draw blood. You may feel a slight pinch, but it’s over quickly. The blood is then sent to a lab for analysis.
What the Results Mean
Results are compared to a general reference range, but individual ranges can vary by lab. High or low levels may signal conditions like hyperestrogenism, ovarian tumors, or menopause-related changes.
Reference range
NCBI: NSE 0-17 ng/mLN/A
No special preparation usually required. Stay well hydrated. Inform your healthcare provider of all medications and supplements you are taking.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
Estrogen levels can indicate reproductive health, bone health, and potential hormonal disorders. High levels may suggest tumors or thyroid issues, while low levels could relate to early menopause, ovarian dysfunction, or certain medications.
Short name
Estrogen Level
Frequently asked questions
What does a high estrogen level mean?
What does a low estrogen level mean?
How often should I get this test?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 17, 2026. · Read our editorial policy