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Estrone and Creatinine, Urine and Stool

Published: August 9, 2026Updated: August 16, 2026

This test measures estrone, an estrogen, and creatinine in urine and stool samples. The results may help evaluate estrogen production or hormone balance.

Quick summary

["Estrone and creatinine results can provide information about estrogen activity and help account for differences in sample concentration."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
34299-8
Short code
Estrone/Creat Ur-sRto
Synonyms
Estrone/Creat Ur-sRto
Category
kidney
Sample
urine
Container
Sterile urine container
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
10 mL
Stability
Room temperature: 2h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
0
Lipemia max
0
Icterus max
0
TAT
4–24 hours
Order
routine

What is this test?

Estrone is a form of estrogen, a hormone involved in female reproductive development and other hormonal functions. Creatinine is a breakdown product that is often measured alongside hormones to help account for variations in urine or stool concentration.

Why might I need this test?

A clinician may order this test when evaluating estrogen production, hormonal balance, or changes related to reproductive or endocrine conditions. The reason for testing and the way the results are interpreted depend on the symptoms, medical history, and specimen used.

How is the test performed?

The laboratory analyzes urine and stool samples for estrone and creatinine using validated testing methods. The report identifies the specimen type and the amount or concentration of each substance measured.

How do I prepare for the test?

Follow the collection instructions provided by the laboratory or your clinician. Urine and stool should be collected in the designated clean containers, and the collection time, date, and any medication or supplement use may need to be reported.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

An elevated or reduced estrone result may reflect differences in estrogen production, metabolism, menstrual or reproductive status, medications, or other hormonal influences. Creatinine can help show how concentrated the specimen is, but an abnormal value in urine or stool is interpreted in the context of the specific test and the person's symptoms. Results should not be interpreted independently without guidance from a qualified clinician.

Short name

Estrone and Creatinine

Frequently asked questions

What does an estrone result measure?
It measures the amount or concentration of estrone, one of the body's estrogen hormones. Estrone can be produced by the ovaries and by conversion of other hormones in peripheral tissues.
Why is creatinine measured with estrone?
Creatinine may be used to help account for how concentrated or dilute a urine or stool sample is. Its role depends on the laboratory's testing method and the specimen being reported.
Do medications or supplements affect these results?
Hormonal medications, other medicines, and some supplements can affect estrogen measurements. Tell your clinician about everything you take, and do not stop prescribed treatment without medical advice.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy