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Ethambutol Serum Concentration (Quantitative)

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of ethambutol, a medication used to treat tuberculosis, in your blood serum. It helps your healthcare provider monitor your drug levels to ensure proper dosing and avoid potential side effects.

Quick summary

["Your ethambutol levels help balance effectiveness and safety during tuberculosis treatment."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
25195-9
Short code
Ethambutol Islt Slgr Mcbct AB 10.0
Synonyms
Ethambutol Islt Slgr Mcbct AB 10.0
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
method-for-slow-growing-mycobacteria-antibiotic-concentration-at-ug-ml
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Is Done

Your doctor may order this test if you’re taking ethambutol to treat tuberculosis. It helps assess whether your dose is working well in your body and whether you need adjustments to prevent low blood levels (which could make the drug less effective) or high levels (which could cause vision problems).

What to Expect Before the Test

No special preparation is needed. You’ll provide a blood sample, usually drawn from a vein in your arm. The process is quick and typically painless.

What the Results Mean

Results are compared to a general reference range for ethambutol in serum. Low levels may indicate insufficient absorption or drug interactions, while very high levels could signal toxicity. Your doctor will interpret results in the context of your treatment plan.

Common Reasons for Monitoring

Doctors monitor ethambutol levels to prevent vision changes (like blurred or reduced vision) caused by high drug concentrations. It also ensures the medication remains effective against tuberculosis bacteria.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Ethambutol is a key antibiotic for tuberculosis treatment, but its effectiveness depends on maintaining safe blood levels. Low levels may lead to treatment failure, while high levels can damage your optic nerve, causing vision loss. Regular monitoring helps balance these risks.

Short name

Ethambutol Level

Frequently asked questions

Why might my doctor order this test if I’m already taking ethambutol?
Your doctor may order this test periodically to check if your dose is appropriate, especially if you have kidney issues (which can affect drug clearance) or if you’re taking other medications that might interact with ethambutol.
What are the most common side effects of ethambutol, and how does this test help prevent them?
Ethambutol can cause vision problems like blurred or reduced vision in some people. This test helps detect high blood levels that could contribute to these side effects, allowing your doctor to adjust your dose if needed.
Can I eat or drink anything before this blood test?
You can eat and drink normally before the test unless your doctor specifies otherwise. No fasting is required for this blood draw.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy