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Ethambutol concentration in serum/plasma (quantitative drug level)

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of the medication ethambutol in your blood. Ethambutol is used to treat tuberculosis and may be prescribed as part of a multi-drug regimen.

Quick summary

["Your ethambutol level helps doctors check if the drug is working properly and adjust your dose if needed."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
25230-4
Short code
Ethambutol Islt Slgr Mcbct AB 2.5
Synonyms
Ethambutol Islt Slgr Mcbct AB 2.5
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
method-for-slow-growing-mycobacteria-antibiotic-concentration-at-ug-ml
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Is Done

Your healthcare provider may order this test if you’re taking ethambutol to treat tuberculosis. It helps ensure the drug is at an effective level in your blood without causing too much of an effect, which could be harmful. This is especially important if you’re taking other medications or have certain health conditions.

How the Test Works

A small blood sample is taken from a vein in your arm. The sample is then analyzed to measure the concentration of ethambutol in your serum or plasma using a sensitive laboratory method.

What to Expect Before the Test

No special preparation is usually needed, but you may be asked to stop taking certain medications or supplements for a short time before the test if instructed by your doctor. Avoid eating or drinking anything for at least 8 hours before the test if directed.

What to Expect During the Test

The blood draw is quick and typically painless. You may feel a slight pinch or discomfort, but most people tolerate it well. You can usually return to your normal activities immediately afterward.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Ethambutol levels help monitor your treatment for tuberculosis. Too little drug may mean the infection isn’t fully controlled, while too much could increase the risk of side effects like vision changes or nerve damage. Regular testing ensures your dose is optimized for safety and effectiveness.

Short name

Ethambutol Level

Frequently asked questions

When might I need this test?
Your doctor may order this test if you’re taking ethambutol for tuberculosis, during your treatment to check levels, or if you have concerns about how the drug is working in your body.
What do my results mean?
Results are typically reported as a concentration value (e.g., micrograms per milliliter). Your doctor will interpret these results in relation to your specific situation, including your weight, kidney function, and other medications.
Can I eat or drink before this test?
Follow your doctor’s instructions—some patients may need to fast for 8 hours before the test, while others may not. Always check with your healthcare provider to avoid interfering with the test results.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy