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Ethylene Glycol Concentration (Serum or Plasma)

Published: August 9, 2026Updated: August 17, 2026

This test measures the amount of ethylene glycol, a toxic substance found in antifreeze, in your blood. High levels can be dangerous and require immediate medical attention.

Quick summary

["Ethylene glycol poisoning can be life-threatening; prompt detection is critical."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 17, 2026Editorial policy

Key facts at a glance

LOINC
109665-0
Short code
Ethylene Glycol Msmt Gast
Synonyms
Ethylene Glycol Msmt Gast
Category
glucose
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Ref low
10
Ref high
40
Critical range
— – 500 N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
84484
SNOMED
302774002
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why Is This Test Done?

Your healthcare provider may order this test if you’ve ingested antifreeze or other ethylene glycol-containing products, or if you show symptoms like confusion, nausea, vomiting, or difficulty breathing. It’s also used in cases of suspected poisoning or unexplained metabolic disturbances.

What to Expect During the Test

A small blood sample is drawn from a vein in your arm. You may feel a slight pinch, but it usually doesn’t cause discomfort. The sample is sent to a lab for analysis.

How the Test Results Are Interpreted

Results are compared to known toxic levels of ethylene glycol. Very high levels may indicate poisoning, while borderline or low levels may prompt further investigation or monitoring.

Symptoms and Warning Signs

Ethylene glycol poisoning can cause symptoms within hours, including severe headache, dizziness, rapid breathing, seizures, or even coma. If you suspect poisoning, seek emergency care immediately.

Reference range

Adult: 10-40 U/LN/A

Specimen: serum

No special preparation required. Avoid fatty meals before the test if possible.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Ethylene glycol poisoning can damage organs like the kidneys and liver, and may lead to metabolic acidosis (a dangerous buildup of acid in the blood). Early detection and treatment with antidotes (like fomepizole or ethanol) improve outcomes.

Short name

Ethylene Glycol Level

Frequently asked questions

What causes high ethylene glycol levels in the blood?
High levels are most commonly due to accidental or intentional ingestion of antifreeze, antifreeze-based products, or other ethylene glycol-containing substances. Rarely, it may occur in people with certain medical conditions affecting metabolism.
How soon after exposure should I expect test results?
Results typically take 1–3 business days, depending on lab processing times. Your healthcare provider will discuss next steps based on the outcome, especially if poisoning is suspected.
Can I drink water before or after the test?
Yes, you can drink water as usual unless instructed otherwise by your provider. Avoid alcohol or other substances that might affect test results, but this does not apply to ethylene glycol poisoning.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 17, 2026. · Read our editorial policy