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Ethylene Glycol Concentration (Serum/Plasma)

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of ethylene glycol, a toxic substance found in antifreeze and other chemicals, in your blood. It helps doctors diagnose poisoning or monitor exposure.

Quick summary

["Detecting ethylene glycol poisoning early can save your life by guiding urgent medical treatment."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
5646-5
Short code
Ethylene Glycol SerPlBld-mCnc
Synonyms
Ethylene Glycol SerPlBld-mCnc
Category
glucose
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Matters

Ethylene glycol poisoning is a medical emergency. This test helps healthcare providers determine if you’ve been exposed to dangerous levels of the substance, which can cause severe health issues like kidney failure, coma, or even death if untreated. Early detection allows for prompt treatment, such as dialysis or antidotes.

What to Expect Before the Test

You may be asked to fast for a few hours before your blood is drawn, depending on your doctor’s instructions. The test involves a simple blood sample taken from a vein in your arm. It usually takes a few minutes, and you may feel slight discomfort but no lasting effects.

Possible Causes of Testing

Your doctor may order this test if you’ve been exposed to ethylene glycol through ingestion (e.g., antifreeze, cleaning products), or if you have symptoms like confusion, vomiting, rapid breathing, or seizures. It’s also used in cases of suspected poisoning in children or adults.

What the Results Mean

Results are reported as a mass concentration in your blood. High levels indicate poisoning, but your doctor will interpret the result in relation to your symptoms, medical history, and other tests. Treatment depends on the severity of exposure.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Ethylene Glycol Level

Frequently asked questions

What symptoms might I experience if my test is abnormal?
If your ethylene glycol level is elevated, you may experience symptoms like nausea, vomiting, confusion, difficulty breathing, seizures, or kidney problems. Severe poisoning can lead to coma or death without immediate medical attention. Symptoms may appear within hours of exposure.
How soon should I seek help if I suspect poisoning?
Seek emergency medical care immediately if you or someone else has ingested ethylene glycol or has symptoms like confusion, rapid breathing, or vomiting. Do not wait to see if symptoms worsen—poisoning can be life-threatening.
Can I prevent ethylene glycol poisoning?
Yes! Keep ethylene glycol-containing products (like antifreeze) locked away from children and pets. Never drink antifreeze or any household chemicals. If you suspect exposure, call a poison control center or seek emergency care right away.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy