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Ethylene Glycol Concentration (Serum)

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of ethylene glycol, a toxic substance found in antifreeze and other products, in your blood serum. It helps doctors diagnose ethylene glycol poisoning.

Quick summary

["Detecting ethylene glycol poisoning early can save your life."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
22734-8
Short code
Ethylene Glycol Spec-sCnc
Synonyms
Ethylene Glycol Spec-sCnc
Category
glucose
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Matters

Ethylene glycol poisoning is a medical emergency. If you suspect exposure—such as drinking antifreeze or other ethylene glycol-containing products—this test helps determine the severity and guides urgent treatment. Symptoms like confusion, vomiting, and seizures can appear within hours, so prompt testing is critical.

How the Test Works

Your blood serum is collected and analyzed using a specialized laboratory method to detect ethylene glycol. The result tells healthcare providers how much of the substance is in your system, helping them decide on the right care, such as dialysis or antidote treatment.

Symptoms of Exposure

Ethylene glycol poisoning can cause symptoms like nausea, dizziness, rapid breathing, or even kidney failure if untreated. If you or someone else has ingested ethylene glycol, seek emergency medical attention immediately, as this test is often part of the diagnostic process.

When You Might Need This Test

Your doctor may order this test if you have symptoms of poisoning, such as confusion, seizures, or signs of kidney problems. It’s also used in cases of suspected accidental or intentional exposure to ethylene glycol-containing products.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance

Short name

Ethylene Glycol Level

Frequently asked questions

What does a high level of ethylene glycol mean?
A high level indicates poisoning, which requires immediate medical attention. Your doctor will use the result to determine the severity of exposure and guide treatment, such as dialysis or administration of an antidote like fomepizole.
What if the test is normal?
If the test is normal, it means there is no detectable ethylene glycol in your blood at the time of testing. However, poisoning can develop quickly, so if you suspect exposure, follow up with your doctor even if initial results are negative.
How soon will I get results?
Results are typically available within 24 hours, depending on lab processing times. Your doctor will discuss the findings with you during your follow-up visit.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy