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Epinephrine (Adrenaline) in Urine (Total 24-Hour Collection)

Published: August 9, 2026Updated: August 16, 2026

This test measures the total amount of epinephrine, a natural chemical your body produces to help respond to stress or excitement, over a 24-hour period through your urine.

Quick summary

["Helps assess how your body handles stress-related hormones over time."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
108363-3
Short code
Etilefrine Msmt Ur
Synonyms
Etilefrine Msmt Ur
Category
chemistry
Sample
urine
Container
Sterile urine container
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
10 mL
Stability
Room temperature: 2h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
0
Lipemia max
0
Icterus max
0
TAT
4–24 hours
Order
routine

Why This Test Is Done

Your doctor may order this test if they suspect conditions like pheochromocytoma (a tumor affecting hormone production), anxiety disorders, or other stress-related conditions that affect hormone levels. It can also help diagnose or monitor conditions affecting the adrenal glands or nervous system.

What to Expect Before the Test

You’ll collect all your urine over a 24-hour period, starting after you wake up in the morning. Store the urine in a refrigerator and return it to your doctor’s office or lab by the next morning. Avoid certain medications that can affect results, such as some blood pressure drugs.

What Happens During the Test

No special preparation is needed beyond collecting urine samples. The lab will analyze the total volume and measure the epinephrine content in your urine sample.

What the Results Mean

Higher-than-normal levels may indicate conditions like pheochromocytoma or excessive stress. Lower-than-normal levels might suggest hormonal imbalances or other underlying health issues. Your doctor will interpret the results in the context of your medical history and other tests.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Epinephrine levels in urine are used to diagnose or monitor conditions that involve abnormal hormone production or stress responses. Elevated levels can point to tumors in the adrenal glands or other adrenal-related disorders. This test is particularly useful for detecting pheochromocytoma, a rare but serious tumor that can cause high blood pressure and other symptoms.

Short name

Urine Epinephrine (24h)

Frequently asked questions

What causes elevated urine epinephrine levels?
Elevated urine epinephrine levels can be caused by conditions such as pheochromocytoma (a tumor affecting hormone production), severe anxiety or stress, certain medications, or even excessive physical activity. It may also be linked to conditions affecting the adrenal glands or nervous system.
Can diet or lifestyle affect this test?
Yes, diet and lifestyle can influence results. Avoid caffeine, nicotine, and certain medications that may affect hormone levels before the test. Stressful activities or emotional states can also temporarily alter hormone production, so it’s important to follow your doctor’s instructions for preparation.
How often is this test repeated?
The frequency depends on your diagnosis and treatment plan. Your doctor may recommend repeating the test if initial results are abnormal or if symptoms persist. Follow-up tests might be scheduled every few months or as needed to monitor progress or adjust treatment.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy