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Etiocholanolone/Creatinine Ratio, Urine

Published: August 9, 2026Updated: August 16, 2026

This urine test measures the ratio of etiocholanolone, a steroid hormone breakdown product, to creatinine, which helps account for differences in urine concentration.

Quick summary

["The ratio adjusts urinary etiocholanolone for urine concentration and may help evaluate steroid metabolism."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
30508-6
Short code
Etiocholanolone/Creat Ur
Synonyms
Etiocholanolone/Creat Ur
Category
kidney
Sample
urine
Container
Sterile urine container
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
10 mL
Stability
Room temperature: 2h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
0
Lipemia max
0
Icterus max
0
TAT
4–24 hours
Order
routine

What is this test?

This test measures etiocholanolone and creatinine in urine and calculates their ratio. Etiocholanolone is a breakdown product of steroid hormones, while creatinine is used as a marker of urine concentration.

Why might I need this test?

A clinician may order this test as part of an evaluation of adrenal steroid production or metabolism. The creatinine ratio can make the etiocholanolone result less dependent on how concentrated or dilute the urine sample is.

How is the test performed?

A urine specimen is collected according to the laboratory's instructions. The laboratory measures etiocholanolone and creatinine and calculates the etiocholanolone-to-creatinine ratio.

How do I prepare for the test?

Follow the urine collection instructions provided by your healthcare professional and tell the laboratory about medicines or supplements you are taking. If a timed collection is requested, collect all urine for the specified period and record the total volume.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

A higher or lower ratio may reflect changes in steroid hormone production or metabolism, medication effects, or conditions that affect the liver or adrenal glands. Urine concentration and incomplete collection can also influence the result, so it should be interpreted by a clinician alongside symptoms and other tests.

Short name

Urinary etiocholanolone-to-creatinine ratio

Frequently asked questions

Why is creatinine included in this test?
Creatinine helps show how concentrated the urine is. Dividing or comparing etiocholanolone with creatinine reduces the effect of variations in urine concentration.
Is this the same as a blood test for etiocholanolone?
No. This test uses a urine specimen and reports a ratio, whereas a blood test would measure etiocholanolone in the bloodstream.
Do I need to collect urine for a specific number of hours?
That depends on the instructions from your clinician or laboratory. A single urine sample may be used, or a timed collection such as a 24-hour collection may be requested.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy