Autoantibody Profile to Screen for Systemic Lupus Erythematosus (SLE) and Related Autoimmune Conditions
This blood test measures several antibodies that may indicate an autoimmune condition, such as lupus or other inflammatory diseases.
["This screening helps identify potential autoimmune activity in your body."]
Key facts at a glance
- LOINC
- 97911-2
- Short code
- ETP p FVIII Ab PPP Chro-AUC
- Synonyms
- ETP p FVIII Ab PPP Chro-AUC
- Category
- chemistry
- Sample
- plasma
- Container
- Lavender-top (EDTA) or Green-top (Heparin)
- Units
- N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Method
- chromo
- Specimen volume
- 5 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
- Hemolysis max
- 500
- Lipemia max
- 1000
- Icterus max
- 500
- TAT
- 4–24 hours
- Order
- routine
What This Test Measures
The test detects the presence of specific autoantibodies, including those that may target nuclear components (e.g., anti-dsDNA, anti-Smith), connective tissue proteins (e.g., anti-Ro/SSA, anti-La/SSB), and other markers associated with autoimmune diseases. These antibodies are part of your immune system’s response to healthy cells, which can occur in conditions like lupus, rheumatoid arthritis, or mixed connective tissue disease.
Why It’s Done
Your healthcare provider may order this test if you have symptoms like joint pain, fatigue, rash, fever, or other signs of inflammation. It can also be used as part of a routine check for individuals at higher risk of autoimmune diseases.
Sample and Preparation
A small blood sample is drawn from your arm. The sample is processed to separate serum (liquid part of blood without clots) for testing. No special preparation is needed, but fasting may be advised for some related tests if included in the panel.
What to Expect
You may feel slight discomfort or bruising at the injection site, but the procedure takes only a few minutes. Results can take several days to a week, depending on lab processing.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
Positive results for certain autoantibodies may suggest an autoimmune condition and guide further testing or treatment. However, many healthy people test positive for some autoantibodies, so results should be interpreted by a healthcare provider in the context of your symptoms and medical history. Negative results do not definitively rule out autoimmune disease.
Short name
Autoimmune Antibody Panel (Screen)
Frequently asked questions
What does a positive result mean?
Can I eat or drink before this test?
How long will I wait for results?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy