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Total IgE (Immunoglobulin E) Level

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of Immunoglobulin E (IgE) in your blood. IgE is a type of antibody that plays a role in allergic reactions and responses to parasites.

Quick summary

IgE levels help identify allergies or immune responses to certain triggers.

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
61325-7
Short code
European Hornet IgE/IgE total %
Synonyms
European Hornet IgE/IgE total %
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What Is Immunoglobulin E (IgE)?

IgE is a protein produced by your immune system in response to allergens (substances like pollen, dust, or certain foods) or parasitic infections. While IgE is normally present in small amounts, elevated levels can signal an allergic reaction or hypersensitivity.

Why Might You Need This Test?

Your doctor may order this test if you have symptoms like sneezing, itching, hives, or breathing difficulties that suggest allergies. It can also help diagnose conditions like asthma, eczema, or certain parasitic infections.

How Is the Test Performed?

A small blood sample is taken from a vein in your arm. The blood is then sent to a lab for analysis using an immunoassay method to measure IgE levels.

What Do Results Mean?

Results are typically reported in International Units per milliliter (IU/mL). Higher than normal levels may indicate allergies, asthma, or other immune-related conditions. Lower levels might suggest a reduced immune response to allergens.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance: Elevated IgE Levels

Short name

IgE Total

Frequently asked questions

How long does it take to get results from this test?
Results are usually available within 1 to 3 business days, depending on your lab’s processing time.
Can IgE levels change over time?
Yes, IgE levels can fluctuate based on exposure to allergens, infections, or treatments like allergy medications or immunotherapy.
Is there anything I should avoid before the test?
No special preparations are needed, but inform your doctor about any medications you’re taking, as some may affect results.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy