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Hemoglobin A1c (HbA1c) with 24-hour urine collection for albumin-to-creatinine ratio (ACR) measurement

Published: August 9, 2026Updated: August 16, 2026

This test measures the average blood sugar levels over the past 2–3 months by analyzing hemoglobin A1c, while also checking for protein in urine to assess kidney function.

Quick summary

Helps track diabetes management and kidney health in people with diabetes.

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
90095-1
Short code
EVENTMANAGINGGROUPATLEADDEPARTMENTORAGENCY
Synonyms
—
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
86038
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Matters for Diabetes Care

Hemoglobin A1c (HbA1c) reflects your blood sugar control over time, giving doctors a clearer picture than daily glucose checks alone. This test is especially useful for long-term diabetes management, helping prevent complications like nerve damage or kidney issues.

Understanding the Urine Test Component

The urine portion of this test measures albumin (a protein) relative to creatinine (a waste product). High albumin levels in urine can signal kidney strain, which is common in people with diabetes. This test helps identify early kidney damage, even if blood tests alone don’t show it.

How the Test Works: Two Parts Combined

Your blood is drawn to measure HbA1c, while a urine sample is collected over 24 hours to check for protein loss. The lab compares albumin and creatinine levels to calculate the albumin-to-creatinine ratio (ACR), which is expressed as a ratio or percentage.

What to Expect Before the Test

No special preparation is needed for HbA1c, but you may be asked to collect a 24-hour urine sample by timing your urine output in a container. Drink plenty of water to help with urine flow, but avoid excessive salt or protein-rich foods that day.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance: Diabetes and Kidney Health Link

Frequently asked questions

What Does an Abnormal HbA1c or Urine Test Mean?
An elevated HbA1c suggests your blood sugar has been consistently high, while a high urine albumin/creatinine ratio may indicate early kidney problems. Neither result alone is definitive—your doctor will review both with your overall health and symptoms.
Can I Fast Before This Test?
No fasting is required for HbA1c, but you should avoid heavy meals or sugary drinks before your blood draw. For the urine test, standard hydration is advised, but no special diet restrictions apply beyond typical 24-hour urine collection guidelines.
How Often Should I Get This Test?
Typically recommended every 3–6 months for people with diabetes, depending on your blood sugar control and kidney health. Your doctor may adjust frequency based on your HbA1c levels, urine test results, and other health factors.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy