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Stool Occult Blood Test (Immunochemical) – Qualitative

Published: August 9, 2026Updated: August 16, 2026

This test detects hidden (occult) blood in your stool using an immunoassay method. It helps identify gastrointestinal bleeding that may not be visibly apparent.

Quick summary

["A positive result may signal an underlying issue like ulcers, polyps, or other gastrointestinal conditions requiring further evaluation."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
45249-0
Short code
Evidence of TB resis
Synonyms
Evidence of TB resis
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
reported
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Is Done

Doctors may recommend this test if you have symptoms like unexplained fatigue, black or tarry stools, or unexplained anemia. It’s also used as a screening tool in certain high-risk groups, such as those with a family history of colorectal cancer.

How the Test Works

A small sample of your stool is applied to special test cards. The immunoassay detects hidden blood proteins (hemoglobin) that indicate bleeding in the digestive tract, providing a qualitative yes/no result.

Preparation

No special preparation is needed, but you should avoid certain foods or medications that may interfere with results, such as red meat, vitamin C supplements, or certain blood-thinning drugs. Collect a fresh stool sample in the morning.

What to Expect

The test is quick and painless. You’ll apply a sample to a card, which is then processed in a lab. Results are typically available within 24 hours.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

A positive result suggests the presence of gastrointestinal bleeding, which could be caused by conditions like peptic ulcers, colorectal cancer, diverticulosis, or hemorrhoids. Further testing, such as colonoscopy or endoscopy, may be needed to determine the cause and guide treatment. A negative result does not rule out bleeding entirely, especially if symptoms persist.

Short name

Hemoccult II (qualitative stool test)

Frequently asked questions

What Does a Positive Result Mean?
A positive result indicates hidden blood in your stool, which may signal an underlying gastrointestinal issue. Your doctor will discuss next steps, such as additional tests or follow-up care, based on your symptoms and medical history.
What If I Have a Negative Result?
A negative result means no visible blood was detected in this sample, but it does not rule out bleeding entirely. If you continue to experience symptoms like unexplained fatigue or changes in bowel habits, further evaluation may be recommended.
How Often Should I Get This Test?
The frequency depends on your health status and risk factors. Your doctor may recommend this test annually for high-risk individuals (e.g., those with a family history of colorectal cancer) or as part of routine screening if you have symptoms.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy