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C-reactive protein (CRP) concentration, serum/plasma

Published: August 9, 2026Updated: August 16, 2026

This test measures the level of C-reactive protein, a substance produced by the liver in response to inflammation in your body.

Quick summary

["CRP helps identify and monitor inflammation, often used to check for infections or other inflammatory conditions."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
94838-0
Short code
EV RNA Amn Ql NAA+probe
Synonyms
EV RNA Amn Ql NAA+probe
Category
chemistry
Sample
fluid
Container
Sterile tube
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
probe-amp-tar
Specimen volume
2-5 mL
Stability
Room temperature: 2h, Refrigerated: 24h
Hemolysis max
300
TAT
4–24 hours
Order
routine

Why CRP Testing Matters

CRP is a marker that signals your body’s immune response. High levels may indicate infections, autoimmune diseases, or other inflammatory processes. Your doctor may order this test to assess risk for conditions like heart disease or to monitor treatment progress for conditions such as rheumatoid arthritis or infections like pneumonia.

What to Expect Before the Test

No special preparation is needed, but you may be asked to fast for 8–12 hours before the test if it’s part of a broader metabolic or liver panel. Bring any medications you’re currently taking, as some may affect results.

Common Uses of CRP Testing

Doctors often use CRP to evaluate suspected infections (e.g., urinary tract infections, sepsis), track chronic inflammatory diseases (e.g., lupus, inflammatory bowel disease), or assess cardiovascular risk. It can also guide decisions about starting or adjusting medications.

How Results Are Interpreted

Results are typically reported in milligrams per liter (mg/L). While reference ranges vary by lab, very high levels (above 10 mg/L) often signal severe inflammation or infection. Your doctor will interpret results in the context of your symptoms and medical history.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance

Short name

CRP (Serum/Plasma)

Frequently asked questions

What could cause elevated CRP levels?
Elevated CRP can result from infections (bacterial, viral, or fungal), injuries, surgeries, or autoimmune diseases. Chronic conditions like heart disease, diabetes, or certain cancers may also lead to higher CRP levels over time. Your doctor will consider your overall health and symptoms to determine the cause.
How often should I get this test?
Frequency depends on your health status. If you have a chronic condition (e.g., heart disease, arthritis), your doctor may recommend periodic CRP testing to monitor inflammation. If you’re asymptomatic, it’s usually not routinely recommended unless symptoms arise.
Can lifestyle changes affect CRP levels?
Yes! Reducing inflammation through diet (e.g., Mediterranean diet), exercise, stress management, and avoiding smoking can lower CRP levels. If you suspect lifestyle changes are influencing your results, discuss this with your healthcare provider.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy