: Excess Residual Cytoplasm (Neutrophil Fluorescence Reduction) Measurement
: This test measures the amount of leftover cytoplasm in neutrophils, a type of white blood cell, using a fluorescence-based method. It is a specialized laboratory measurement that may help evaluate how neutrophils mature and function.
[": The test quantifies excess residual cytoplasm in neutrophils as an indicator of cell maturation and health."]
Key facts at a glance
- LOINC
- 90047-2
- Short code
- Excess residual cytoplasm NFr Smn
- Synonyms
- Excess residual cytoplasm NFr Smn
- Category
- chemistry
- Sample
- serum
- Container
- Red-top tube (SST)
- Units
- N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Specimen volume
- 5 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
- Hemolysis max
- 500
- Lipemia max
- 1000
- Icterus max
- 500
- TAT
- 4–24 hours
- Order
- routine
: What Is Being Measured
: Neutrophils are white blood cells that help fight infection. As they mature, they normally lose most of their internal fluid (cytoplasm). This test estimates how much cytoplasm remains, referred to as excess residual cytoplasm, using a fluorescence signal that is reduced when less cytoplasm is present.
: How the Test Works
: A blood sample is processed in the laboratory so that neutrophils can be examined with a fluorescence-based measurement. The instrument detects a signal related to the cytoplasm content of these cells. The term "fluorescence reduction" indicates that the measured signal changes depending on how much residual cytoplasm is present.
: Why Your Doctor May Order It
: This is not a routine test. It may be used in specialized settings to study neutrophil maturation or to support evaluation of certain blood or immune conditions. Your doctor will interpret the result alongside your medical history, other blood counts, and additional tests.
: What the Results Mean
: Results are reported by the laboratory using its own method and reference information, so the meaning depends on the specific testing system. An abnormal value alone does not diagnose a condition. Your care team will explain what your result suggests in the context of your overall health.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
: Changes in neutrophil cytoplasm and maturation can be seen in some blood disorders and immune conditions, so this measurement may provide supportive information. However, it is a specialized research or reference-laboratory type of test, and its clinical usefulness depends on the specific method and the broader clinical picture.
Short name
: NONE
Frequently asked questions
: Is this a standard blood test?
: Does an abnormal result mean I have a disease?
: How is the sample collected?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy