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Serum Insulin — Exclusion-Criteria Entry (PhenX)

Published: August 9, 2026Updated: August 16, 2026

This entry appears to refer to insulin measured in serum. “Exclusion criteria” and “PhenX” are not standard parts of a routine insulin test and may identify a special protocol.

Quick summary

["The test measures insulin in a blood sample, but the special exclusion-criteria qualifier may affect how the result should be used."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
66505-9
Short code
Exclusion criteria serum insulin PhenX
Synonyms
Exclusion criteria serum insulin PhenX
Category
liver
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Ref low
2.6
Ref high
24.9
Fasting
true
Population
adult
Sex
all
Age range
18–65 years
Method
phenx
CPT
83525
SNOMED
413618004
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

What is this test?

This test measures the amount of insulin in serum, the liquid portion of blood. Insulin is a hormone that helps the body regulate blood sugar by moving glucose into cells and encouraging energy storage.

Why might I need this test?

A serum insulin test may be ordered to help assess how the body is handling glucose. It can be used in the evaluation of low or high blood sugar, insulin resistance, diabetes, or conditions involving insulin production, depending on the clinical situation.

How is the test performed?

Blood is collected through a vein, and the serum is separated from the clotted sample. The insulin level is then measured using a laboratory method. The “PhenX” qualifier in this entry is not clearly defined and should be confirmed with the ordering laboratory.

How do I prepare for the test?

Follow the preparation instructions provided by your clinician or laboratory. The test may be performed while fasting or at a specified time, and insulin levels can be affected by meals and glucose intake. Do not change medications or restrict food unless your clinician directs you to do so.

Reference range

Fasting: 2.6-24.9 μIU/mLN/A

Specimen: serum

No special preparation usually required. Stay well hydrated. Inform your healthcare provider of all medications and supplements you are taking.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

An insulin result is interpreted together with the blood glucose level, timing of the sample, symptoms, medications, and other laboratory findings. Insulin that is higher or lower than expected may reflect fasting, food intake, diabetes or insulin resistance, medication effects, or less common disorders of insulin production or action. The term “exclusion criteria” may mean that this result is being used in a specific decision rule, so the result should not be interpreted independently without that context.

Short name

Serum insulin

Frequently asked questions

Is this the same as a routine insulin blood test?
It appears to measure serum insulin, but the additional “exclusion criteria” and “PhenX” terms suggest a specialized entry or protocol. Ask the ordering laboratory whether any special timing or interpretation rules apply.
Do I need to fast before this test?
That depends on the specific order. Fasting and timed insulin testing are used in different situations, so follow your clinician’s instructions rather than assuming a fasting or nonfasting preparation.
Can a serum insulin result diagnose diabetes?
No single insulin result usually establishes a diagnosis by itself. Insulin is generally interpreted with glucose and other clinical information, and the reference range may depend on the laboratory and testing conditions.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy