Electrophoresis of Serum Proteins (Qualitative or Semi-Quantitative)
This test measures the different types of proteins in your blood using gel electrophoresis, a method that separates proteins based on size and electrical charge. It helps identify abnormalities in protein distribution, which may indicate conditions like infections, liver disease, or certain cancers.
["This test helps doctors diagnose and monitor conditions affecting protein balance in your blood."]
Key facts at a glance
- LOINC
- 65904-5
- Short code
- Eye fields photo L eye Ret dig photog
- Synonyms
- Eye fields photo L eye Ret dig photog
- Category
- chemistry
- Sample
- serum
- Container
- Red-top tube (SST)
- Units
- N/A
- Fasting
- false
- Population
- adult
- Sex
- all
- Age range
- 18–65 years
- Method
- retinal-digital-photography
- Specimen volume
- 5 mL
- Stability
- Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
- Hemolysis max
- 500
- Lipemia max
- 1000
- Icterus max
- 500
- TAT
- 4–24 hours
- Order
- routine
What Does This Test Measure?
Electrophoresis separates blood proteins into five main bands: albumin, alpha-1 globulins, alpha-2 globulins, beta globulins, and gamma globulins (including immunoglobulins). Each band represents different protein groups, and their relative sizes can reveal underlying health issues.
Why Might You Need This Test?
Your doctor may order this test to investigate symptoms like unexplained weight loss, fatigue, swelling, or to evaluate conditions such as multiple myeloma, autoimmune diseases, liver or kidney disorders, or infections.
Common Conditions Monitored
Abnormal protein patterns can signal conditions like multiple myeloma (excess gamma globulins), liver disease (reduced albumin), or chronic infections (increased acute-phase proteins). It’s also used in screening for hereditary disorders like alpha-1 antitrypsin deficiency.
Sample Collection and Preparation
A blood sample is drawn from a vein, typically in your arm. The blood is then processed to separate serum (the liquid part after clotting) for analysis. No special preparation is needed, but fasting may be advised depending on your doctor’s instructions.
Clinical interpretation
How abnormal results are interpreted and what conditions they suggest.
Clinical Significance
Short name
Serum Protein Electrophoresis
Frequently asked questions
How long does it take to get results from this test?
Can I eat or drink before this test?
What are the typical reference ranges for protein bands?
Sources
- 1
- 2Lab Tests OnlineSource
- 3
Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.
This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.
This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.
If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.
Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy