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Serum or plasma concentration of free fatty acids (unsaturated, medium-chain length)

Published: August 9, 2026Updated: August 16, 2026

This test measures levels of certain free fatty acids in your blood, which play a role in energy production and metabolism. It may be used to assess lipid metabolism or identify conditions affecting fat breakdown.

Quick summary

["Understanding your fatty acid profile can help doctors diagnose or monitor metabolic or genetic disorders."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
91681-7
Short code
F9 gene Fam Mut Anl Amn/CVS
Synonyms
F9 gene Fam Mut Anl Amn/CVS
Category
chemistry
Sample
fluid
Container
Sterile tube
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
molgen
Specimen volume
2-5 mL
Stability
Room temperature: 2h, Refrigerated: 24h
Hemolysis max
300
TAT
4–24 hours
Order
routine

Why This Test Might Be Ordered

Your healthcare provider may recommend this test if you have symptoms or conditions linked to abnormal fatty acid metabolism, such as unexplained fatigue, muscle weakness, or signs of metabolic syndrome. It could also be part of a broader evaluation for genetic disorders affecting fat metabolism, like carnitine palmitoyltransferase (CPT) deficiencies.

What to Expect Before the Test

No special preparation is typically needed, but you may be asked to fast for 8–12 hours before drawing blood. Avoid excessive alcohol or strenuous activity 24 hours prior. If you’re on medications that affect fats (e.g., statins), let your provider know.

What the Results Mean

Results show the concentration of specific free fatty acids in your bloodstream. Abnormal levels may indicate metabolic imbalances, genetic disorders, or other health concerns that require further medical evaluation.

Common Conditions Monitored

This test helps identify or track conditions like medium-chain acyl-CoA dehydrogenase (MCAD) deficiency, mitochondrial disorders, or other rare metabolic syndromes. It may also support diagnosis in patients with unexplained lipid abnormalities or fasting intolerance.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Free medium-chain unsaturated fatty acid profile

Frequently asked questions

How often will I need this test?
The frequency depends on your health status and treatment plan. If you have a known metabolic disorder, your doctor may order this test periodically to monitor changes in your fatty acid levels. Otherwise, it’s usually done as needed for specific symptoms or investigations.
What are the typical reference ranges?
Reference ranges vary by lab and fatty acid type. Your results will be compared to your own baseline and clinical context, not a single set of general values. Your healthcare provider will interpret the results in relation to your overall health.
Can diet or exercise affect these results?
Yes, diet (especially fat intake), exercise, and medications can influence fatty acid levels. Avoid high-fat meals or extreme dietary changes before testing, and follow your provider’s instructions for optimal results.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy