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Vitamin D binding protein (DBP) concentration

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of vitamin D binding protein in your blood, which helps transport vitamin D and other substances in your body. It may be used to assess vitamin D metabolism or related conditions.

Quick summary

["Understanding your DBP levels can help doctors evaluate how well your body processes vitamin D."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
27814-3
Short code
Fact VII+Fact X Act/Nor PPP
Synonyms
Fact VII+Fact X Act/Nor PPP
Category
chemistry
Sample
plasma
Container
Lavender-top (EDTA) or Green-top (Heparin)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
coag
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Might Be Ordered

Your healthcare provider may order this test if you have symptoms or risk factors for vitamin D-related disorders, such as chronic kidney disease, certain genetic conditions, or unexplained metabolic issues. It may also be part of a broader evaluation for conditions affecting protein metabolism or vitamin D balance.

What to Expect Before the Test

No special preparation is typically needed. You may have a blood sample drawn from a vein in your arm, similar to other blood tests. If you’re on blood thinners or have a history of bleeding disorders, let your doctor know.

What the Results Mean

Results provide a measure of DBP concentration in your blood. While reference ranges can vary by lab, abnormal levels may indicate conditions like vitamin D disorders, kidney disease, or protein-related metabolic issues. Your doctor will interpret results in the context of your overall health.

Common Conditions Linked to DBP Levels

High or low DBP levels may be associated with conditions such as chronic kidney disease, certain genetic disorders (like familial chylomicronemia syndrome), or metabolic disorders affecting protein transport. It’s not typically used alone for diagnosis but may support broader evaluations.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance

Short name

DBP Level

Frequently asked questions

What causes DBP levels to change?
DBP levels can be influenced by kidney function, genetic factors, certain medications (like steroids), or metabolic disorders. Chronic kidney disease often leads to altered DBP production, while genetic conditions may cause elevated or reduced levels. Always discuss any medications or health conditions with your doctor before testing.
How often should I get this test?
The frequency depends on your health status and symptoms. If you have a known condition affecting DBP (e.g., kidney disease or a genetic disorder), your doctor may recommend regular monitoring. Otherwise, this test is usually ordered as needed for specific concerns.
Can diet or lifestyle affect DBP levels?
Dietary factors like vitamin D intake or protein-rich foods may indirectly influence DBP-related metabolism, but DBP itself is primarily produced by the liver and kidneys. Lifestyle changes (e.g., exercise, hydration) may support overall health but don’t directly alter DBP levels unless linked to underlying conditions.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy