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Vitamin D binding protein (DBP) concentration

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of vitamin D binding protein in your blood, which helps transport vitamin D and other substances in your body.

Quick summary

["Understanding your DBP levels can help assess vitamin D metabolism and related health risks."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
3197-1
Short code
Fact VII PPP-aCnc
Synonyms
Fact VII PPP-aCnc
Category
chemistry
Sample
plasma
Container
Lavender-top (EDTA) or Green-top (Heparin)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
coag
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Your healthcare provider may order this test to measure your diastolic blood pressure (DBP) as part of a routine checkup or to help diagnose and manage high blood pressure, heart disease, kidney problems, or other conditions that can affect your heart and blood vessels.

Your healthcare provider may recommend this test if you have symptoms or conditions linked to vitamin D deficiency, such as bone pain, fatigue, or muscle weakness. It may also be used in cases where vitamin D levels are unclear or when monitoring vitamin D-related disorders.

Before the test, avoid coffee, tea, energy drinks, smoking, and strenuous exercise for at least 30 minutes. Try to empty your bladder, sit quietly for about five minutes, and wear a shirt with a loose sleeve so the blood pressure cuff can be placed comfortably on your upper arm.

No special preparation is needed for this blood test. You may be asked to fast for 8–12 hours before drawing blood, but this depends on your provider’s instructions. Wear comfortable clothing and plan to stay near the testing site for about 15 minutes.

A healthcare professional will wrap a blood pressure cuff around your upper arm and inflate it. As the cuff slowly deflates, the device measures the pressure in your arteries while your heart rests between beats. This resting pressure is your DBP, reported in millimeters of mercury (mmHg).

A small sample of blood is drawn from a vein in your arm. The blood is then analyzed to measure the concentration of vitamin D binding protein, typically using a blood chemistry method like immunoassay or nephelometry.

Results are reported as two numbers, and the second, lower number is your DBP. A typical healthy reading is below 80 mmHg. A higher value may suggest hypertension, while a lower value can point to other issues, so your provider will interpret your result together with your overall health and medical history.

Results are reported as a mass concentration (e.g., grams per liter). While reference ranges vary by lab, abnormal levels may indicate conditions affecting vitamin D metabolism, such as kidney disease or certain genetic disorders.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance

Short name

DBP level

Frequently asked questions

Vitamin D binding protein plays a key role in transporting vitamin D and other hormones in your bloodstream. Abnormal levels may suggest underlying health concerns, such as kidney dysfunction or hereditary disorders affecting protein function, which could impact vitamin D availability and related health outcomes.
A low DBP, generally below 60 mmHg, means the pressure in your arteries when your heart rests between beats is lower than usual. Some people feel fine, but others may notice dizziness, lightheadedness, fainting, or fatigue. Possible causes include certain medications, dehydration, or heart problems, so tell your doctor about any symptoms you have.
A low DBP level may indicate conditions like kidney disease or certain genetic disorders that affect protein metabolism. It could also be part of broader testing for vitamin D-related issues, though further evaluation may be needed to determine the exact cause.
For most adults, blood pressure is checked at least once a year during a routine office visit. If your readings are borderline high, you have been diagnosed with hypertension, or you take blood pressure medication, your provider may recommend checks every few weeks or months. Always follow the schedule your healthcare team gives you.
Your provider will determine how often you need this test based on your health status, symptoms, or other medical conditions. Regular monitoring may be recommended if you have chronic kidney disease, vitamin D deficiency, or other related conditions.
Dietary factors or supplements that influence vitamin D levels (such as vitamin D or calcium supplements) may indirectly affect vitamin D metabolism, but they do not directly alter DBP protein levels. Always follow your provider’s advice regarding supplements.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy