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Fasting Total Cholesterol with Lipid Profile (Serum)

Published: August 9, 2026Updated: August 16, 2026

This test measures your cholesterol levels, including total cholesterol, as well as key components of your lipid profile, which help assess heart health.

Quick summary

["Cholesterol and lipid levels are critical for preventing cardiovascular risks."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
10522-1
Short code
Fact XIII Ag Tiss Ql ImStn
Synonyms
Fact XIII Ag Tiss Ql ImStn
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Method
immune-stain
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Matters

Cholesterol is a waxy substance your body needs to function, but having too much can build up in your arteries, increasing the risk of heart disease or stroke. This test helps doctors evaluate your overall lipid health and identify potential risks early.

What to Expect Before the Test

You’ll need to fast (not eat or drink anything except water) for several hours before your blood is drawn. Your doctor or lab will provide specific instructions to follow.

What the Test Measures

This test includes measurements for total cholesterol, which is the sum of different types of cholesterol (LDL, HDL, and triglycerides) in your blood. While total cholesterol alone isn’t enough to assess risk, it’s a key part of a broader lipid profile.

How Results Are Used

Your results will help your healthcare provider determine if your cholesterol levels are within a healthy range or if lifestyle changes or medication may be needed to manage your risk of heart disease.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Clinical Significance

Frequently asked questions

How often should I get this test?
Typically, doctors recommend cholesterol screening every 4–5 years for adults without known risk factors. If you have risk factors (like high blood pressure, diabetes, or a family history of heart disease), your doctor may advise more frequent testing.
What does a ‘normal’ result mean?
There’s no single ‘normal’ number for total cholesterol alone—it depends on your age, gender, and overall health. Your doctor will interpret results in relation to your personal risk factors and may suggest additional tests (like LDL or HDL) if needed.
Can diet or exercise change my cholesterol results?
Yes! Small, sustainable lifestyle changes—such as eating heart-healthy foods (like fruits, vegetables, and whole grains), reducing saturated fats, and staying physically active—can significantly improve cholesterol levels over time.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy