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Serum or Plasma Mass Concentration of Digoxin (or Related Cardiac Glycoside)

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of a heart medication called digoxin in your blood. It helps doctors check if your dose is safe and effective.

Quick summary

["Digoxin helps control heart rhythm but can be dangerous if levels are too high."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
63207-5
Short code
False ragweed IgG-mCnc
Synonyms
False ragweed IgG-mCnc
Category
chemistry
Sample
serum
Container
Red-top tube (SST)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
CPT
82784
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Matters

Digoxin is used to treat certain heart conditions, such as irregular heartbeats or heart failure. Your doctor may order this test to monitor your response to the medication and prevent side effects like low heart rate or nausea.

How the Test Works

A blood sample is taken from a vein in your arm. The lab uses a sensitive test to measure the exact amount of digoxin in your serum or plasma. This helps doctors determine if your dose is working properly or if adjustments are needed.

What to Expect Before the Test

You can eat and drink normally before the test, but let your doctor or lab technician know if you’re taking any other medications, especially those that might affect heart function. Avoid heavy exercise or stress before the test if instructed.

What to Expect During the Test

The test is quick and painless. A small needle will be inserted into your arm, and a few drops of blood will be drawn. You may feel a slight pinch, but it usually takes only a few seconds. The blood sample is then sent to the lab for analysis.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Digoxin Level

Frequently asked questions

How often should I get this test?
Your doctor will determine how often you need this test based on your medical condition, how long you’ve been taking digoxin, and whether you have kidney problems. Typically, it may be done every few weeks or months to check your levels.
What does a normal range mean?
There isn’t a single ‘normal’ range for digoxin because it varies depending on your health, age, and other medications. Your doctor will use the results to guide your treatment plan, not a fixed number.
Can I eat or drink anything before the test?
Yes, you can eat and drink normally before the test unless your doctor advises otherwise. Avoid alcohol or caffeine in excess, as they may affect your heart rate temporarily.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy