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Fatty Acid Profile (Long Chain Fatty Acids) in Serum

Published: August 9, 2026Updated: August 16, 2026

This test measures levels of long-chain fatty acids in your blood serum, which can help assess metabolic health, lipid processing, or potential genetic conditions affecting fat metabolism.

Quick summary

["Long-chain fatty acids are critical for energy production and cell function; abnormal levels may signal metabolic disorders or genetic conditions."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
111444-6
Short code
Fat Msmt Stl
Synonyms
Fat Msmt Stl
Category
chemistry
Sample
stool
Container
Clean container
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
5 g
Stability
Refrigerated: 24h, Frozen: 7d
TAT
4–24 hours
Order
routine

Why This Test Might Be Ordered

Your healthcare provider may recommend this test if you have symptoms like unexplained fatigue, muscle weakness, or if they suspect conditions such as fatty acid oxidation disorders, mitochondrial diseases, or other metabolic syndromes. It may also be part of a broader evaluation for unexplained lipid abnormalities or genetic testing.

What to Expect Before the Test

No special preparation is typically needed, but you may be asked to fast for 8–12 hours before the draw if your lab requires it. Bring any medications you’re currently taking to your appointment.

What the Test Involves

A blood sample will be drawn from a vein in your arm by a healthcare professional. The sample is collected in a special tube and sent to the lab for analysis.

What the Results Mean

Results show the concentration of specific long-chain fatty acids in your serum. Abnormal patterns may indicate metabolic dysfunction, but interpretation depends on clinical context and comparison to your symptoms or family history.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

Elevated or altered levels of long-chain fatty acids can signal metabolic disorders, such as carnitine palmitoyltransferase (CPT) deficiencies or other fatty acid oxidation defects. These conditions may affect energy production, muscle function, or growth. Your provider will correlate results with your symptoms and medical history to guide diagnosis or treatment planning.

Short name

Long Chain Fatty Acids (LCFA) Serum

Frequently asked questions

What causes abnormal fatty acid levels?
Abnormal fatty acid levels can result from genetic mutations affecting fat metabolism, certain medications, or underlying conditions like diabetes, thyroid disorders, or liver disease. If you have a family history of metabolic disorders, this test may be part of preventive screening.
How long will I need to wait for results?
Results are typically available within 1–3 business days, depending on your lab’s processing time. Your provider will discuss findings with you during a follow-up visit.
Can I eat or drink before this test?
Follow your provider’s instructions, but generally, fasting for 8–12 hours before blood draw is recommended unless otherwise directed. Avoid alcohol and heavy meals to ensure accurate results.
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This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy