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Fibrinogen concentration in plasma

Published: August 9, 2026Updated: August 16, 2026

This test measures the amount of fibrinogen, a protein in your blood that helps blood clot. It’s often checked when you have bleeding problems, clotting disorders, or certain medical conditions.

Quick summary

["Fibrinogen helps control bleeding and supports blood clotting—your levels may be checked for health or safety reasons."]

Medically reviewed by WellAlly Editorial TeamLast reviewed August 16, 2026Editorial policy

Key facts at a glance

LOINC
42493-7
Short code
FCA Fract Plas-mCnc
Synonyms
FCA Fract Plas-mCnc
Category
chemistry
Sample
plasma
Container
Lavender-top (EDTA) or Green-top (Heparin)
Units
N/A
Fasting
false
Population
adult
Sex
all
Age range
18–65 years
Specimen volume
5 mL
Stability
Room temperature: 4h, Refrigerated: 24h, Frozen: 7d
Hemolysis max
500
Lipemia max
1000
Icterus max
500
TAT
4–24 hours
Order
routine

Why This Test Is Done

Your doctor may order this test to evaluate your risk of bleeding too much (hemorrhage) or forming dangerous blood clots (thrombosis). It’s also used to monitor conditions like liver disease, kidney problems, or certain cancers that can affect fibrinogen levels.

What to Expect Before the Test

No special preparation is needed. You may have a small needle inserted into your arm or vein to draw a blood sample. If you’re on blood thinners, let your doctor know before the test.

How the Test Results Are Interpreted

Results are compared to a general range for healthy adults, but your doctor will consider your overall health, symptoms, and medical history. Very low or very high levels may signal underlying issues.

Common Conditions Affecting Results

Low fibrinogen levels might indicate liver disease, severe infections, or conditions like disseminated intravascular coagulation (DIC). High levels could be linked to inflammation, pregnancy, or certain blood disorders.

Clinical interpretation

How abnormal results are interpreted and what conditions they suggest.

◆Associated findings1

Short name

Plasma Fibrinogen

Frequently asked questions

What causes my fibrinogen levels to be checked?
Your doctor may order this test if you have symptoms like unusual bruising, excessive bleeding, or signs of clotting problems (e.g., swelling, pain from clots). It’s also part of routine checks for conditions like liver disease or cancer.
Do I need to avoid certain foods or medications before this test?
No dietary restrictions are typically required. If you’re on blood thinners (like warfarin), tell your doctor before the test to ensure safety.
Will I feel pain or discomfort during the blood draw?
Most people experience only mild discomfort or a slight pinch during the needle insertion. Some may feel tired afterward, but it’s usually brief.
  1. 1
    MedlinePlus — Laboratory TestsSource
  2. 2
    Lab Tests OnlineSource
  3. 3
    Mayo Clinic — Tests & ProceduresSource

Click any link to access the full source. PubMed Central (PMC) links provide free full-text access.

This information is for educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment.

Medical Disclaimer

This content is for general informational and educational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always seek the guidance of a qualified healthcare provider with any questions you have about a medical condition, and never disregard professional medical advice or delay seeking it because of something you read here.

If you think you may have a medical emergency, call your local emergency number or go to the nearest emergency department immediately.

Medically reviewed by WellAlly Editorial Team Last reviewed August 16, 2026. · Read our editorial policy